(Q28270716)

2

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D Nicholson

3

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N Thornberry

4

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A Rosen

5

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L Casciola-Rosen

The baculovirus p35 protein inhibits Fas- and tumor necrosis factor-induced apoptosis.

6

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language of work or name

English

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publication date

April 1998

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published in

Immunity

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volume

8

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page(s)

451-60

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issue

4

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cites work

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Inhibition of ICE family proteases by baculovirus antiapoptotic protein p35.

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Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes

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DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis

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Apopain/CPP32 cleaves proteins that are essential for cellular repair: a fundamental principle of apoptotic death

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Selective cleavage of nuclear autoantigens during CD95 (Fas/APO-1)-mediated T cell apoptosis

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Activation of the apoptotic protease CPP32 by cytotoxic T-cell-derived granzyme B.

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X-linked IAP is a direct inhibitor of cell-death proteases

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Granzyme B/Perforin-Mediated Apoptosis of Jurkat Cells Results in Cleavage of Poly(ADP-ribose) Polymerase to the 89-kDa Apoptotic Fragment and Less Abundant 64-kDa Fragment

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New Paradigm for Lymphocyte Granule-mediated Cytotoxicity

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Sequential activation of three distinct ICE-like activities in Fas-ligated Jurkat cells

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Cytotoxic lymphocytes require granzyme B for the rapid induction of DNA fragmentation and apoptosis in allogeneic target cells.

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Inhibition of death receptor signals by cellular FLIP

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Programmed cell death in animal development

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Regulation of the Fas apoptotic cell death pathway by Abl.

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Caspases: killer proteases

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Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

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Human and murine cytotoxic T lymphocyte serine proteases: subsite mapping with peptide thioester substrates and inhibition of enzyme activity and cytolysis by isocoumarins

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Binding of granzyme B in the nucleus of target cells. Recognition of an 80-kilodalton protein

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Cytolytic T cell granules. Isolation, structural, biochemical, and functional characterization

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Caspases: intracellular signaling by proteolysis

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Target cell lysis by CTL granule exocytosis is independent of ICE/Ced-3 family proteases

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Purification of three cytotoxic lymphocyte granule serine proteases that induce apoptosis through distinct substrate and target cell interactions

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Granzyme B (GraB) autonomously crosses the cell membrane and perforin initiates apoptosis and GraB nuclear localization.

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FLAME-1, a novel FADD-like anti-apoptotic molecule that regulates Fas/TNFR1-induced apoptosis

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Viral FLICE-inhibitory proteins (FLIPs) prevent apoptosis induced by death receptors

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Apoptosis in the pathogenesis and treatment of disease

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A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis

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Localization of granzyme B in the nucleus. A putative role in the mechanism of cytotoxic lymphocyte-mediated apoptosis

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Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein

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