(Q28272256)

1

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Roya Babaei-Jadidi

2

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Anas Saadeddin

3

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Sina Hossaini

5

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Mohammed Abuzinadah

6

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Ningning Li

7

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Wakkas Fadhil

8

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Mohammad Ilyas

9

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Dominique Bonnet

10

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Abdolrahman S Nateri

Wnt/beta-catenin signaling in cancer stemness and malignant behavior

11

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language of work or name

English

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publication date

October 2012

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published in

Stem Cells

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volume

30

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issue

10

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page(s)

2076-87

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cites work

1 reference

Wnt signalling in stem cells and cancer

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A role for Wnt signalling in self-renewal of haematopoietic stem cells

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Wnt activity defines colon cancer stem cells and is regulated by the microenvironment

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Crypt stem cells as the cells-of-origin of intestinal cancer

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O2 regulates stem cells through Wnt/β-catenin signalling.

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Functional expression cloning of Nanog, a pluripotency sustaining factor in embryonic stem cells

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Nanog and transcriptional networks in embryonic stem cell pluripotency

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Eleven daughters of NANOG

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Transcriptional properties of human NANOG1 and NANOG2 in acute leukemic cells.

21 January 2018

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The pluripotency homeobox gene NANOG is expressed in human germ cell tumors

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Differential expression of nanog1 and nanogp8 in colon cancer cells

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Human embryonic stem cell genes OCT4, NANOG, STELLAR, and GDF3 are expressed in both seminoma and breast carcinoma

21 January 2018

1 reference

Functional evidence that the self-renewal gene NANOG regulates human tumor development

21 January 2018

1 reference

Comprehensive analysis of the clinical significance of inducing pluripotent stemness-related gene expression in colorectal cancer cells

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NANOG regulates glioma stem cells and is essential in vivo acting in a cross-functional network with GLI1 and p53.

21 January 2018

1 reference

NANOGP8 is a retrogene expressed in cancers

21 January 2018

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Role of the murine reprogramming factors in the induction of pluripotency

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Hedgehog controls neural stem cells through p53-independent regulation of Nanog

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Beta-catenin up-regulates Nanog expression through interaction with Oct-3/4 in embryonic stem cells

21 January 2018

1 reference

NANOG is a direct target of TGFbeta/activin-mediated SMAD signaling in human ESCs

21 January 2018

1 reference

Loss of WNT-TCF addiction and enhancement of HH-GLI1 signalling define the metastatic transition of human colon carcinomas

21 January 2018

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Over-expression of Nanog predicts tumor progression and poor prognosis in colorectal cancer

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An embryonic stem cell-like gene expression signature in poorly differentiated aggressive human tumors

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Module map of stem cell genes guides creation of epithelial cancer stem cells

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Octamer and Sox elements are required for transcriptional cis regulation of Nanog gene expression

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Transcriptional regulation of nanog by OCT4 and SOX2.

21 January 2018

1 reference

A Tcf/Lef element within the enhancer region of the human NANOG gene plays a role in promoter activation

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1 reference

Repression of Nanog gene transcription by Tcf3 limits embryonic stem cell self-renewal

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Isolation and characterization of the murine Nanog gene promoter

21 January 2018

1 reference

Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas

21 January 2018

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Interaction of phosphorylated c-Jun with TCF4 regulates intestinal cancer development

21 January 2018

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Protocol for the fast chromatin immunoprecipitation (ChIP) method

21 January 2018

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The Src family of tyrosine kinases is important for embryonic stem cell self-renewal

21 January 2018

1 reference

Downregulation of NANOG induces differentiation of human embryonic stem cells to extraembryonic lineages

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Apc modulates embryonic stem-cell differentiation by controlling the dosage of beta-catenin signaling

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1 reference

Teratocarcinomas and mammalian embryogenesis

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1 reference

Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

21 January 2018

1 reference

Exploring the role of cancer stem cells in radioresistance

21 January 2018

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DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

21 January 2018

1 reference

Two new protocols to enhance the production and isolation of human induced pluripotent stem cell lines

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Defined factors induce reprogramming of gastrointestinal cancer cells

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Nucleotide sequence of the 5'-flanking region of the murine ornithine decarboxylase gene.

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1 reference

A UTF1-based selection system for stable homogeneously pluripotent human embryonic stem cell cultures

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Gli1, downregulated in colorectal cancers, inhibits proliferation of colon cancer cells involving Wnt signalling activation

21 January 2018

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Suppressing Wnt signaling by the hedgehog pathway through sFRP-1

21 January 2018

1 reference

Human colon cancer epithelial cells harbour active HEDGEHOG-GLI signalling that is essential for tumour growth, recurrence, metastasis and stem cell survival and expansion

21 January 2018

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The ubiquitin ligase SCFFbw7 antagonizes apoptotic JNK signaling

21 January 2018

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The links between transcription, beta-catenin/JNK signaling, and carcinogenesis

21 January 2018

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OCT4 spliced variant OCT4B1 is expressed in human colorectal cancer

21 January 2018

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Atypical expression and distribution of embryonic stem cell marker, OCT4, in human lung adenocarcinoma.

21 January 2018

1 reference

PML targeting eradicates quiescent leukaemia-initiating cells

21 January 2018

1 reference

Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis

21 January 2018

1 reference

Notch post-translationally regulates β-catenin protein in stem and progenitor cells

21 January 2018

1 reference