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Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

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Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo (English)

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M Kozak

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1

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English

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March 1984

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308

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5956

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page(s)

241-6

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How do eucaryotic ribosomes select initiation regions in messenger RNA?

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Proteins specified by avian erythroblastosis virus: coding region localization and identification of a previously undetected erb-B polypeptide

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Translation of insulin-related polypeptides from messenger RNAs with tandemly reiterated copies of the ribosome binding site

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Possible role of flanking nucleotides in recognition of the AUG initiator codon by eukaryotic ribosomes

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Eukaryotic ribosomes can recognize preproinsulin initiation codons irrespective of their position relative to the 5' end of mRNA

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SV40-transformed simian cells support the replication of early SV40 mutants

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Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

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Use of recombinant DNA technology to program eukaryotic cells to synthesize rat proinsulin: a rapid expression assay for cloned genes

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Expression of simian virus 40-rat preproinsulin recombinants in monkey kidney cells: use of preproinsulin RNA processing signals

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Deletion loop mutagenesis: a novel method for the construction of point mutations using deletion mutants

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An in vitro method generating base substitutions in preselected regions of plasmid DNA: Application to structural analysis of the replication origin of the Escherichia coli K-12 chromosome

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Directed mutagenesis of DNA cloned in filamentous phage: influence of hemimethylated GATC sites on marker recovery from restriction fragments

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Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

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10.1038/308241A0

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1000426968

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6700727

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(Q28272278)

Point mutations close to the AUG initiator codon affect the efficiency of translation of rat preproinsulin in vivo

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