(Q28278294)

English

Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule ends

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scholarly article

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Antiproliferative mechanism of action of cryptophycin-52: kinetic stabilization of microtubule dynamics by high-affinity binding to microtubule ends (English)

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author name string

D Panda

1

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K DeLuca

2

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D Williams

3

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M A Jordan

4

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L Wilson

5

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language of work or name

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publication date

4 August 1998

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Proceedings of the National Academy of Sciences of the United States of America

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95

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16

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9313-8

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Mechanism of action of the unusually potent microtubule inhibitor cryptophycin 1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

20 March 2017

Microtubule treadmilling in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

20 March 2017

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

20 March 2017

Cryptophycin: a new antimicrotubule agent active against drug-resistant cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

20 March 2017

Kinetochores capture astral microtubules during chromosome attachment to the mitotic spindle: direct visualization in live newt lung cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

20 March 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

2 references

https://api.crossref.org/works/10.1073/PNAS.95.16.9313

22 April 2017

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

22 April 2017

Dynamic instability of microtubule growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

7 April 2017

Stabilization of microtubule dynamics by estramustine by binding to a novel site in tubulin: a possible mechanistic basis for its antitumor action

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Vinblastine suppresses dynamics of individual microtubules in living interphase cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Observation and quantification of individual microtubule behavior in vivo: microtubule dynamics are cell-type specific

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

How the transition frequencies of microtubule dynamic instability (nucleation, catastrophe, and rescue) regulate microtubule dynamics in interphase and mitosis: analysis using a Monte Carlo computer simulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Mechanism of mitotic block and inhibition of cell proliferation by taxol at low concentrations

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Microtubule treadmills--possible molecular machinery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Dynamic instability of individual microtubules analyzed by video light microscopy: rate constants and transition frequencies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

29 September 2017

Microtubule dynamics: taking aim at a moving target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Differential effects of vinblastine on polymerization and dynamics at opposite microtubule ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Kinetic stabilization of microtubule dynamic instability in vitro by vinblastine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Mechanism of inhibition of cell proliferation by Vinca alkaloids.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=21335

2 June 2018

Substoichiometric binding of taxol suppresses microtubule dynamics.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Mechanism of action cryptophycin. Interaction with the Vinca alkaloid domain of tubulin.

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Kinetic Stabilization of Microtubule Dynamics at Steady State in Vitro by Substoichiometric Concentrations of Tubulin-Colchicine Complex

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Identification of a protein that interacts with tubulin dimers and increases the catastrophe rate of microtubules

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Visualization of the dynamic instability of individual microtubules by dark-field microscopy

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Total Structures of Cryptophycins, Potent Antitumor Depsipeptides from the Blue-Green Alga Nostoc sp. Strain GSV 224

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Structure determination, conformational analysis, chemical stability studies, and antitumor evaluation of the cryptophycins. Isolation of 18 new analogs from Nostoc sp. strain GSV 224

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Interaction of cryptophycin 1 with tubulin and microtubules

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.95.16.9313

21 January 2018

Characterization of the interaction of cryptophycin 1 with tubulin: binding in the Vinca domain, competitive inhibition of dolastatin 10 binding, and an unusual aggregation reaction

1 reference

https://pubmed.ncbi.nlm.nih.gov/9689077

12 December 2020

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10.1073/PNAS.95.16.9313

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1998PNAS...95.9313P

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