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Regulation of ion channels by secreted Klotho: mechanisms and implications
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instance of
scholarly article
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review article
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stated in
Europe PubMed Central
title
Regulation of ion channels by secreted Klotho: mechanisms and implications
(English)
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author name string
Chou-Long Huang
series ordinal
1
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language of work or name
English
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publication date
May 2010
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published in
Kidney International
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volume
77
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issue
10
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page(s)
855-60
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cites work
Mutation of the mouse klotho gene leads to a syndrome resembling ageing
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Suppression of aging in mice by the hormone Klotho
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of a novel mouse membrane-bound family 1 glycosidase-like protein, which carries an atypical active site structure
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Secreted Klotho protein in sera and CSF: implication for post-translational cleavage in release of Klotho protein from cell membrane
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Insulin stimulates the cleavage and release of the extracellular domain of Klotho by ADAM10 and ADAM17
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of the mouse klotho gene and its two transcripts encoding membrane and secreted protein
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https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glycosidase mechanisms
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
Klotho is a novel beta-glucuronidase capable of hydrolyzing steroid beta-glucuronides
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
Removal of sialic acid involving Klotho causes cell-surface retention of TRPV5 channel via binding to galectin-1
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of renal outer medullary potassium channel and renal K(+) excretion by Klotho
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
The beta-glucuronidase klotho hydrolyzes and activates the TRPV5 channel
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
The beta-glucuronidase klotho exclusively activates the epithelial Ca2+ channels TRPV5 and TRPV6.
1 reference
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
Heparan sulphate proteoglycans fine-tune mammalian physiology
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https://api.crossref.org/works/10.1038%2FKI.2010.73
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Negative regulation of T-cell activation and autoimmunity by Mgat5 N-glycosylation
1 reference
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https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
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Regulation of cytokine receptors by Golgi N-glycan processing and endocytosis.
1 reference
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https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
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Biosynthesis and function of N- and O-substituted sialic acids
1 reference
stated in
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reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
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inferred from DOI database lookup
Identification of linkage-specific sequence motifs in sialyltransferases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dimeric galectin-1 binds with high affinity to alpha2,3-sialylated and non-sialylated terminal N-acetyllactosamine units on surface-bound extended glycans.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dietary and genetic control of glucose transporter 2 glycosylation promotes insulin secretion in suppressing diabetes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
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inferred from DOI database lookup
The Klotho gene family and the endocrine fibroblast growth factors
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
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7 January 2021
based on heuristic
inferred from DOI database lookup
The emerging role of the fibroblast growth factor-23-klotho axis in renal regulation of phosphate homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Regulation of fibroblast growth factor-23 signaling by klotho
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The FGF23-Klotho axis: endocrine regulation of phosphate homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mediation of unusually high concentrations of 1,25-dihydroxyvitamin D in homozygous klotho mutant mice by increased expression of renal 1alpha-hydroxylase gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Klotho
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Klotho prevents renal calcium loss.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein kinase C inhibits caveolae-mediated endocytosis of TRPV5.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo klotho gene transfer ameliorates angiotensin II-induced renal damage
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Angiotensin II inhibits the ROMK-like small conductance K channel in renal cortical collecting duct during dietary potassium restriction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRPC6.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mutation in the TRPC6 cation channel causes familial focal segmental glomerulosclerosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
TRPC6 fulfills a calcineurin signaling circuit during pathologic cardiac remodeling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Severely reduced production of klotho in human chronic renal failure kidney.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Amelioration of progressive renal injury by genetic manipulation of Klotho gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
alpha-Klotho as a regulator of calcium homeostasis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FKI.2010.73
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1038/KI.2010.73
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Dimensions Publication ID
1029308115
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PubMed publication ID
20375979
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ResearchGate publication ID
43073914
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