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Novel cytotoxic agents: epothilones

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Novel cytotoxic agents: epothilones (English)

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Susan Goodin

1

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language of work or name

English

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publication date

15 May 2008

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published in

American Journal of Health-System Pharmacy

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volume

65

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page(s)

S10-5

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issue

10 Suppl 3

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cites work

Extending survival with chemotherapy in metastatic breast cancer

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Novel formulations of taxanes: a review. Old wine in a new bottle?

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Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

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31 March 2020

Microtubule functions

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31 March 2020

Targeting microtubules to inhibit angiogenesis and disrupt tumour vasculature: implications for cancer treatment.

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Targeting the microtubules in breast cancer beyond taxanes: the epothilones

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31 March 2020

The binding mode of epothilone A on alpha,beta-tubulin by electron crystallography

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THE DEVELOPMENT AND CLINICAL UTILITY OF THE TAXANE CLASS OF ANTIMICROTUBULE CHEMOTHERAPY AGENTS

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Mechanisms of action of and resistance to antitubulin agents: microtubule dynamics, drug transport, and cell death

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Estramustine resistance correlates with tau over-expression in human prostatic carcinoma cells

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31 March 2020

Efficacy and safety of ixabepilone, a novel epothilone analogue.

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Development of novel chemotherapeutic agents to evade the mechanisms of multidrug resistance (MDR).

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Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, as first-line therapy in patients with metastatic breast cancer previously treated with anthracycline chemotherapy

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Phase II clinical trial of ixabepilone (BMS-247550), an epothilone B analog, in metastatic and locally advanced breast cancer

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Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Patients With Taxane-Resistant Metastatic Breast Cancer

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Efficacy and safety of ixabepilone (BMS-247550) in a phase II study of patients with advanced breast cancer resistant to an anthracycline, a taxane, and capecitabine

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Multi-institutional randomized phase II trial of the epothilone B analog ixabepilone (BMS-247550) with or without estramustine phosphate in patients with progressive castrate metastatic prostate cancer.

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Ixabepilone (epothilone B analogue BMS-247550) is active in chemotherapy-naive patients with hormone-refractory prostate cancer: a Southwest Oncology Group trial S0111.

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Phase II clinical trial of the epothilone B analog, ixabepilone, in patients with non small-cell lung cancer whose tumors have failed first-line platinum-based chemotherapy

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A Phase II trial of epothilone B analogue BMS-247550 (NSC #710428) ixabepilone, in patients with advanced pancreas cancer: a Southwest Oncology Group study

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Ixabepilone plus capecitabine for metastatic breast cancer progressing after anthracycline and taxane treatment

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https://api.crossref.org/works/10.2146%2FAJHP080089

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31 March 2020

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ResearchGate publication ID

5388964

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(Q28279384)

Novel cytotoxic agents: epothilones

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