(Q28281452)

English

From toxicological problem to therapeutic use: the discovery of the mode of action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug

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Europe PubMed Central

From toxicological problem to therapeutic use: the discovery of the mode of action of 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-cyclohexanedione (NTBC), its toxicology and development as a drug (English)

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author name string

E A Lock

1

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M K Ellis

2

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P Gaskin

3

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M Robinson

4

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T R Auton

5

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W M Provan

6

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L L Smith

7

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M P Prisbylla

8

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L C Mutter

9

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D L Lee

10

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language of work or name

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publication date

August 1998

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Journal of Inherited Metabolic Disease

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21

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5

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498-506

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On the enzymic defects in hereditary tyrosinemia

1 reference

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Effects of ingestion of disproportionate amounts of amino acids

1 reference

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Purification and some properties of 4-hydroxyphenylpyruvate dioxygenase from Pseudomonas sp. P. J. 874

1 reference

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Response of the lysosomal system of the corneal epithelium to tyrosine-induced cell injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

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Four-hydroxyphenylpyruvic acid oxidase deficiency with normal fumarylacetoacetase: a new variant form of hereditary hypertyrosinemia

1 reference

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Excess dietary tyrosine and corneal lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

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Tyrosinemia II: lessons in molecular pathophysiology

1 reference

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4-Hydroxyphenylpyruvate dioxygenase from human liver

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

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The effect of diet on the ophthalmological, clinical and biochemical aspects of Richner-Hanhart syndrome: a morphological ultrastructural study of the cornea and the conjunctiva.

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Treatment of hereditary tyrosinaemia type I by inhibition of 4-hydroxyphenylpyruvate dioxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

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Inhibition of Barnyardgrass 4-Hydroxyphenylpyruvate Dioxygenase by Sulcotrione

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

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based on heuristic

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Tissue distribution of 2-(2-nitro-4-trifluoromethylbenzoyl)cyclohexane-1-3-dione (NTBC): effect on enzymes involved in tyrosine catabolism and relevance to ocular toxicity in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of 4-hydroxyphenylpyruvate dioxygenase by 2-(2-nitro-4-trifluoromethylbenzoyl)-cyclohexane-1,3-dione and 2-(2-chloro-4-methanesulfonylbenzoyl)-cyclohexane-1,3-dione

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the interaction of 2-[2-nitro-4-(trifluoromethyl)benzoyl]-4,4,6,6,-tetramethyl- cyclohexane-1,3,5-trione with rat hepatic 4-hydroxyphenylpyruvate dioxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chronic Tyrosinemia Associated with 4-Hydroxyphenylpyruvate Dioxygenase Deficiency with Acute Intermittent Ataxia and without Visceral and Bone Involvement

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SC-0051, a 2-benzoyl-cyclohexane-1,3-dione bleaching herbicide, is a potent inhibitor of the enzyme p-hydroxyphenylpyruvate dioxygenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Keratopathy in tyrosinemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Purification and some properties of human 4-hydroxyphenylpyruvate dioxygenase (I)

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

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based on heuristic

inferred from PubMed ID database lookup

Inhibition of phenylalanine hydroxylase, a pterin-requiring monooxygenase, by oudenone and its derivatives

1 reference

https://pubmed.ncbi.nlm.nih.gov/9728330

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1023/A:1005458703363

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