(Q28289761)

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Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1

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Glycogen synthase kinase 3 regulates expression of nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) and inhibits pro-survival function of Nrf1 (English)

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author name string

Madhurima Biswas

1

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Erick K Kwong

2

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Eujean Park

3

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Parminder Nagra

4

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Jefferson Y Chan

5

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language of work or name

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publication date

1 August 2013

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Experimental Cell Research

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319

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13

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1922-31

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1 reference

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Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells

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Glycogen synthase kinase 3: more than a namesake

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Cancer related mutations in NRF2 impair its recognition by Keap1-Cul3 E3 ligase and promote malignancy

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The p65 isoform of Nrf1 is a dominant negative inhibitor of ARE-mediated transcription

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Nrf1 is targeted to the endoplasmic reticulum membrane by an N-terminal transmembrane domain. Inhibition of nuclear translocation and transacting function

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Proapoptotic stimuli induce nuclear accumulation of glycogen synthase kinase-3 beta

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TCF11/Nrf1 overexpression increases the intracellular glutathione level and can transactivate the gamma-glutamylcysteine synthetase (GCS) heavy subunit promoter

1 reference

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The CNC basic leucine zipper factor, Nrf1, is essential for cell survival in response to oxidative stress-inducing agents. Role for Nrf1 in gamma-gcs(l) and gss expression in mouse fibroblasts

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Targeted disruption of the ubiquitous CNC-bZIP transcription factor, Nrf-1, results in anemia and embryonic lethality in mice

1 reference

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Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

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1 reference

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The renaissance of GSK3

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SCF/{beta}-TrCP promotes glycogen synthase kinase 3-dependent degradation of the Nrf2 transcription factor in a Keap1-independent manner.

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High levels of Nrf2 determine chemoresistance in type II endometrial cancer

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2 June 2018

Identifiers

10.1016/J.YEXCR.2013.04.013

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