(Q28290286)

English

Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Phenobarbital indirectly activates the constitutive active androstane receptor (CAR) by inhibition of epidermal growth factor receptor signaling (English)

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

author name string

Shingo Mutoh

1

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Mack Sobhany

2

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Rick Moore

3

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Lalith Perera

4

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Lee Pedersen

5

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Tatsuya Sueyoshi

6

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Masahiko Negishi

7

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

language of work or name

0 references

publication date

7 May 2013

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Science Signaling

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

6

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

274

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

ra31

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

Triclocarban mediates induction of xenobiotic metabolism through activation of the constitutive androstane receptor and the estrogen receptor alpha

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

PXR and CAR in energy metabolism

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

EGF activates its receptor by removing interactions that autoinhibit ectodomain dimerization

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

A crucial role for RACK1 in the regulation of glucose-stimulated IRE1alpha activation in pancreatic beta cells

1 reference

https://api.crossref.org/works/10.1126/SCISIGNAL.2003705

21 April 2017

AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003705

21 April 2017

A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003705

21 April 2017

An insulin-like growth factor 1 receptor inhibitor induces CYP3A4 expression through a pregnane X receptor-independent, noncanonical constitutive androstane receptor-related mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Active ERK1/2 protein interacts with the phosphorylated nuclear constitutive active/androstane receptor (CAR; NR1I3), repressing dephosphorylation and sequestering CAR in the cytoplasm

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Insulin induces swelling-dependent activation of the epidermal growth factor receptor in rat liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Nuclear receptor CAR represses TNFalpha-induced cell death by interacting with the anti-apoptotic GADD45B

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Dephosphorylation of threonine 38 is required for nuclear translocation and activation of human xenobiotic receptor CAR (NR1I3).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Phosphorylation of RACK1 on tyrosine 52 by c-Abl is required for insulin-like growth factor I-mediated regulation of focal adhesion kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

New insights on the xenobiotic-sensing nuclear receptors in liver diseases--CAR and PXR--.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Extracellular signal-regulated kinase is an endogenous signal retaining the nuclear constitutive active/androstane receptor (CAR) in the cytoplasm of mouse primary hepatocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Nuclear receptors CAR and PXR cross talk with FOXO1 to regulate genes that encode drug-metabolizing and gluconeogenic enzymes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

The RACK1 scaffold protein: a dynamic cog in cell response mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

RACK1: a novel substrate for the Src protein-tyrosine kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

Protein tyrosine phosphatase 1B interacts with and is tyrosine phosphorylated by the epidermal growth factor receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5573139

2 June 2018

The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29.

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003705

21 January 2018

Xenobiotic stress induces hepatomegaly and liver tumors via the nuclear receptor constitutive androstane receptor

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003705

21 January 2018

The orphan nuclear receptor constitutive active/androstane receptor is essential for liver tumor promotion by phenobarbital in mice

1 reference

https://api.crossref.org/works/10.1126%2FSCISIGNAL.2003705

21 January 2018

Independent mechanisms for tumor promoters phenobarbital and 12-O-tetradecanoylphorbol-13-acetate in reduction of epidermal growth factor binding by rat hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23652203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin suppresses the induction of CYP2B1 and CYP2B2 gene expression by phenobarbital in adult rat cultured hepatocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/23652203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

DRUG-INDUCED CHANGES IN THE LIVER ENDOPLASMIC RETICULUM: ASSOCIATION WITH DRUG-METABOLIZING ENZYMES

1 reference

https://pubmed.ncbi.nlm.nih.gov/23652203

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1126/SCISIGNAL.2003705

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

2 October 2017

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