(Q28290751)

1

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Pei-Shan Hsieh

2

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Cheng-Tang Chiu

3

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Wai-Ying Chen

Novel mechanism of Wnt signalling inhibition mediated by Dickkopf-1 interaction with LRP6/Arrow

4

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language of work or name

English

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publication date

9 December 2004

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published in

Oncogene

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volume

23

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issue

57

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page(s)

9183-9

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cites work

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A new member of the frizzled family from Drosophila functions as a Wingless receptor

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Regulation of Wnt/LRP signaling by distinct domains of Dickkopf proteins

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Wnt signaling: a common theme in animal development

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Somatic mutations of the beta-catenin gene are frequent in mouse and human hepatocellular carcinomas

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The Wnt antagonist Dickkopf-1 is regulated by Bmp signaling and c-Jun and modulates programmed cell death

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Identification of c-MYC as a target of the APC pathway

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Aberrant caspase-activated DNase (CAD) transcripts in human hepatoma cells

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Reduced expression of the REIC/Dkk-3 gene by promoter-hypermethylation in human tumor cells

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Functional and structural diversity of the human Dickkopf gene family

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Decreased expression of REIC/Dkk-3 in human renal clear cell carcinoma

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Cloning the differences between two complex genomes

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Kremen2 modulates Dickkopf2 activity during Wnt/LRP6 signaling

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Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling

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Beta-catenin is temporally regulated during normal liver development

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A functional genomics approach for the identification of putative tumor suppressor genes: Dickkopf-1 as suppressor of HeLa cell transformation

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Convergence of Wnt, beta-catenin, and cadherin pathways

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Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

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Stabilization of beta-catenin by genetic defects in melanoma cell lines

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AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1

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A REIC gene shows down-regulation in human immortalized cells and human tumor-derived cell lines

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Cadherins as Modulators of Cellular Phenotype

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Isolation and biochemical characterization of the human Dkk-1 homologue, a novel inhibitor of mammalian Wnt signaling

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Genetic and epigenetic alterations of the blood group ABO gene in oral squamous cell carcinoma

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Antiproliferative activity of REIC/Dkk-3 and its significant down-regulation in non-small-cell lung carcinomas

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Overexpression of human Dickkopf-1, an antagonist of wingless/WNT signaling, in human hepatoblastomas and Wilms' tumors.

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7 January 2021