(Q28298983)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452323%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

Definition by functional and structural analysis of two malonyl-CoA sites in carnitine palmitoyltransferase 1A (English)

1 reference

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29 December 2019

4

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29 December 2019

Dolors Serra Cucurull

6

1 reference

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29 December 2019

Paulino Gómez-Puertas

9

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29 December 2019

author name string

Eduardo López-Viñas

1

1 reference

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29 December 2019

Assia Bentebibel

2

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29 December 2019

Chandrashekaran Gurunathan

3

1 reference

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29 December 2019

Dolores de Arriaga

5

1 reference

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29 December 2019

Guillermina Asins

7

1 reference

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29 December 2019

Fausto G Hegardt

8

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29 December 2019

language of work or name

English

0 references

publication date

23 April 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452323%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

29 December 2019

published in

1 reference

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29 December 2019

volume

282

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29 December 2019

issue

25

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29 December 2019

page(s)

18212-18224

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The mitochondrial carnitine palmitoyltransferase system. From concept to molecular analysis

29 December 2019

cites work

1 reference

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High expression of a novel carnitine palmitoyltransferase I like protein in rat brown adipose tissue and heart: isolation and characterization of its cDNA clone

21 January 2018

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A novel brain-expressed protein related to carnitine palmitoyltransferase I

21 January 2018

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Hypothalamic malonyl-CoA triggers mitochondrial biogenesis and oxidative gene expression in skeletal muscle: Role of PGC-1alpha.

21 January 2018

1 reference

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Changes in the ability of malonyl-CoA to inhibit carnitine palmitoyltransferase I activity and to bind to rat liver mitochondria during incubation in vitro. Differences in binding at 0 degree C and 37 degrees C with a fixed concentration of malonyl-

21 January 2018

1 reference

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Time-dependence of inhibition of carnitine palmitoyltransferase I by malonyl-CoA in mitochondria isolated from livers of fed or starved rats. Evidence for transition of the enzyme between states of low and high affinity for malonyl-CoA.

21 January 2018

1 reference

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Binding of malonyl-CoA to isolated mitochondria. Evidence for high- and low-affinity sites in liver and heart and relationship to inhibition of carnitine palmitoyltransferase activity

21 January 2018

1 reference

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Interacting effects of L-carnitine and malonyl-CoA on rat liver carnitine palmitoyltransferase

21 January 2018

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The first 28 N-terminal amino acid residues of human heart muscle carnitine palmitoyltransferase I are essential for malonyl CoA sensitivity and high-affinity binding

21 January 2018

1 reference

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Identification of conserved amino acid residues in rat liver carnitine palmitoyltransferase I critical for malonyl-CoA inhibition. Mutation of methionine 593 abolishes malonyl-CoA inhibition

21 January 2018

1 reference

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Specificity of the interactions between Glu-3, Ser-24, and Gln-30 within the N-terminal segment of rat liver mitochondrial overt carnitine palmitoyltransferase (L-CPT I) in determining the malonyl-CoA sensitivity of the enzyme

21 January 2018

1 reference

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Demonstration of N- and C-terminal domain intramolecular interactions in rat liver carnitine palmitoyltransferase 1 that determine its degree of malonyl-CoA sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700885200

The mitochondrial intermembrane loop region of rat carnitine palmitoyltransferase 1A is a major determinant of its malonyl-CoA sensitivity

21 January 2018

1 reference

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Role of carnitine in hepatic ketogenesis

21 January 2018

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Effects of fasting, adrenalectomy and streptozotocin-diabetes on sensitivity of hepatic carnitine acyltransferase to malonyl CoA.

21 January 2018

1 reference

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Observations on the affinity for carnitine, and malonyl-CoA sensitivity, of carnitine palmitoyltransferase I in animal and human tissues. Demonstration of the presence of malonyl-CoA in non-hepatic tissues of the rat

21 January 2018

1 reference

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Effects of pH on the interaction of substrates and malonyl-CoA with mitochondrial carnitine palmitoyltransferase I.

21 January 2018

1 reference

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Structural model of the catalytic core of carnitine palmitoyltransferase I and carnitine octanoyltransferase (COT): mutation of CPT I histidine 473 and alanine 381 and COT alanine 238 impairs the catalytic activity

21 January 2018

1 reference

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Improving the quality of twilight-zone alignments

21 January 2018

1 reference

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FFAS03: a server for profile--profile sequence alignments

21 January 2018

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Gapped BLAST and PSI-BLAST: a new generation of protein database search programs

21 January 2018

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SCOP database in 2004: refinements integrate structure and sequence family data

21 January 2018

1 reference

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SCOP: a structural classification of proteins database for the investigation of sequences and structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700885200

21 January 2018

The Protein Data Bank

1 reference

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Domain packing and dynamics in the DNA complex of the N-terminal zinc fingers of TFIIIA

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M700885200

Crystal structure of mouse carnitine octanoyltransferase and molecular determinants of substrate selectivity

21 January 2018

1 reference

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Crystal structure of rat carnitine palmitoyltransferase II (CPT-II)

21 January 2018

1 reference

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Protein modelling for all

21 January 2018

1 reference

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ProMod and Swiss-Model: Internet-based tools for automated comparative protein modelling

21 January 2018

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SWISS-MODEL: An automated protein homology-modeling server

21 January 2018

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WHAT IF: a molecular modeling and drug design program

21 January 2018

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SWISS-MODEL and the Swiss-PdbViewer: an environment for comparative protein modeling

21 January 2018

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Automated docking of substrates to proteins by simulated annealing

21 January 2018

1 reference

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Redesign of carnitine acetyltransferase specificity by protein engineering

21 January 2018

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Novel effect of C75 on carnitine palmitoyltransferase I activity and palmitate oxidation

21 January 2018

1 reference

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The crystal structure of carnitine palmitoyltransferase 2 and implications for diabetes treatment

21 January 2018

1 reference

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Scoring docking models with evolutionary information.

21 January 2018

1 reference

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Structural model of carnitine palmitoyltransferase I based on the carnitine acetyltransferase crystal

21 January 2018

1 reference

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Binding of [14C]malonyl-CoA to rat liver mitochondria after blocking of the active site of carnitine palmitoyltransferase I. Displacement of low-affinity binding by palmitoyl-CoA.

21 January 2018

1 reference

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Expression of a cDNA isolated from rat brown adipose tissue and heart identifies the product as the muscle isoform of carnitine palmitoyltransferase I (M-CPT I). M-CPT I is the predominant CPT I isoform expressed in both white (epididymal) and brown

21 January 2018

1 reference

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Pig liver carnitine palmitoyltransferase I, with low Km for carnitine and high sensitivity to malonyl-CoA inhibition, is a natural chimera of rat liver and muscle enzymes

21 January 2018

1 reference

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Functional studies of yeast-expressed human heart muscle carnitine palmitoyltransferase I.

21 January 2018

1 reference

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Effects of incubation at physiological temperatures on the concentration-dependence of [2-14C]malonyl-CoA binding to rat liver mitochondria

21 January 2018

1 reference

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Re-evaluation of the interaction of malonyl-CoA with the rat liver mitochondrial carnitine palmitoyltransferase system by using purified outer membranes

21 January 2018

1 reference

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Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4

21 January 2018

1 reference

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21 January 2018

1 reference

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21 January 2018

Identifiers

DOI

10.1074/JBC.M700885200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17452323%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference