(Q28299076)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

review article

1 reference

title

The blood-brain-barrier in multiple sclerosis: functional roles and therapeutic targeting (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

0 references

0 references

1 reference

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

author name string

Andrés Villa

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

language of work or name

English

0 references

publication date

1 March 2007

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

volume

40

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

page(s)

148-160

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

Transporting therapeutics across the blood-brain barrier

29 December 2019

cites work

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The Dale E. McFarlin Memorial Lecture: the immunology of the multiple sclerosis lesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Junctions between intimately apposed cell membranes in the vertebrate brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Endothelial fenestral diaphragms: a quick-freeze, deep-etch study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Transcytosis of protein through the mammalian cerebral epithelium and endothelium. II. Adsorptive transcytosis of WGA-HRP and the blood-brain and brain-blood barriers

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Astrocyte-endothelial interactions at the blood-brain barrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Synergistic effects of neurons and astrocytes on the differentiation of brain capillary endothelial cells in culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Human blood-derived macrophages enhance barrier function of cultured primary bovine and human brain capillary endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

CD163-positive perivascular macrophages in the human CNS express molecules for antigen recognition and presentation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Occludin: a novel integral membrane protein localizing at tight junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Claudin-1 and -2: novel integral membrane proteins localizing at tight junctions with no sequence similarity to occludin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Tight junctions of the blood-brain barrier: development, composition and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The tight junction protein ZO-1 establishes a link between the transmembrane protein occludin and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

ZO-3, a novel member of the MAGUK protein family found at the tight junction, interacts with ZO-1 and occludin

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Monoclonal antibody 7H6 reacts with a novel tight junction-associated protein distinct from ZO-1, cingulin and ZO-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Junctional adhesion molecules (JAMs): more molecules with dual functions?

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

A heterophilic adhesion mechanism for platelet/endothelial cell adhesion molecule 1 (CD31)

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Interferon-beta directly influences monocyte infiltration into the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Astrocyte-endothelial interaction: physiology and pathology

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Induction of blood-brain barrier properties in immortalized bovine brain endothelial cells by astrocytic factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Decrease in the density of orthogonal arrays of particles in membranes of cultured rat astroglial cells by the brain fibroblast growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Astrocytes induce blood–brain barrier properties in endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Leukocyte infiltration, neuronal degeneration, and neurite outgrowth after ablation of scar-forming, reactive astrocytes in adult transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Neural induction of the blood-brain barrier: still an enigma

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Astrocyte-endothelial interactions and blood-brain barrier permeability

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Migration of Hematogenous Cells Through the Blood-Brain Barrier and the Initiation of CNS Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Alpha4-integrin-VCAM-1 binding mediates G protein-independent capture of encephalitogenic T cell blasts to CNS white matter microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Requirements for passage of T lymphocytes across non-inflamed retinal microvessels

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Perivascular T cells express the pro-inflammatory chemokine RANTES mRNA in multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Chemokines CXCL10 and CCL2: differential involvement in intrathecal inflammation in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Functional expression of the lymphoid chemokines CCL19 (ELC) and CCL 21 (SLC) at the blood-brain barrier suggests their involvement in G-protein-dependent lymphocyte recruitment into the central nervous system during experimental autoimmune encephal

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Expression of CCR7 in multiple sclerosis: implications for CNS immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

CC-chemokine receptor 5 polymorphism and age of onset in familial multiple sclerosis. Multiple Sclerosis Genetics Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The ins and outs of T-lymphocyte trafficking to the CNS: anatomical sites and molecular mechanisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The role of integrins in immune-mediated diseases of the nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

VCAM-1-positive microglia target oligodendrocytes at the border of multiple sclerosis lesions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Intracellular signalling controlling integrin activation in lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Plasminogen activators and matrix metalloproteases, mediators of extracellular proteolysis in inflammatory demyelination of the central nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

T-cell- and macrophage-mediated axon damage in the absence of a CNS-specific immune response: involvement of metalloproteinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Induction of metalloproteinase activity in human T-lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Signal-regulatory protein alpha-CD47 interactions are required for the transmigration of monocytes across cerebral endothelium

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Junctional adhesion molecule, a novel member of the immunoglobulin superfamily that distributes at intercellular junctions and modulates monocyte transmigration

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

CCR1+/CCR5+ mononuclear phagocytes accumulate in the central nervous system of patients with multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Resistance to experimental autoimmune encephalomyelitis in mice lacking the CC chemokine receptor (CCR)2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Vascular endothelial growth factor modulates neutrophil transendothelial migration via up-regulation of interleukin-8 in human brain microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Neutrophil infiltration, glial reaction, and neurological disease in transgenic mice expressing the chemokine N51/KC in oligodendrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Increases in soluble VCAM-1 correlate with a decrease in MRI lesions in multiple sclerosis treated with interferon beta-1b.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Methylprednisolone reduces adhesion molecules in blood and cerebrospinal fluid in patients with MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Anti-alpha4 integrin therapy for multiple sclerosis: mechanisms and rationale.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Prevention of experimental autoimmune encephalomyelitis by antibodies against alpha 4 beta 1 integrin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

A controlled trial of natalizumab for relapsing multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Randomized multicenter trial of natalizumab in acute MS relapses: clinical and MRI effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Natalizumab plus interferon beta-1a for relapsing multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Progressive multifocal leukoencephalopathy complicating treatment with natalizumab and interferon beta-1a for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Progressive multifocal leukoencephalopathy in a patient treated with natalizumab

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Progressive multifocal leukoencephalopathy after natalizumab therapy for Crohn's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Evaluation of patients treated with natalizumab for progressive multifocal leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Therapeutic potential of lovastatin in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Oral simvastatin treatment in relapsing-remitting multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Statins as immunomodulators: comparison with interferon-beta 1b in MS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Statins reduce human blood-brain barrier permeability and restrict leukocyte migration: relevance to multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Lymphocyte Function-Associated Antigen-1 Blockade by Statins: Molecular Basis and Biological Relevance

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Statins selectively inhibit leukocyte function antigen-1 by binding to a novel regulatory integrin site

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Interferon-beta counteracts inflammatory mediator-induced effects on brain endothelial cell tight junction molecules-implications for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Interferon (IFN)-beta 1a and IFN-beta 1b block IFN-gamma-induced disintegration of endothelial junction integrity and barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Antibody-mediated blockade of the CXCR3 chemokine receptor results in diminished recruitment of T helper 1 cells into sites of inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

CXCR3-binding chemokines: novel multifunctional therapeutic targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Antibody targeting of the CC chemokine ligand 5 results in diminished leukocyte infiltration into the central nervous system and reduced neurologic disease in a viral model of multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Effect of steroids on CSF matrix metalloproteinases in multiple sclerosis: relation to blood-brain barrier injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Targeting leukocyte MMPs and transmigration: minocycline as a potential therapy for multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Inhibition of autoimmune encephalomyelitis by a tetracycline.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Minocycline reduces gadolinium-enhancing magnetic resonance imaging lesions in multiple sclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Delivery of therapeutic agents to the central nervous system: the problems and the possibilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Conjugation of brain-derived neurotrophic factor to a blood-brain barrier drug targeting system enables neuroprotection in regional brain ischemia following intravenous injection of the neurotrophin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

New systems for delivery of drugs to the brain in neurological disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Transcriptional activation by tetracyclines in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

PECAM-1 and gelatinase B coexist in vascular cuffs of multiple sclerosis lesions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Natalizumab effects on immune cell responses in multiple sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

Control of TH2 polarization by the chemokine monocyte chemoattractant protein-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1080%2F08916930601183522

10.1080/08916930601183522

21 January 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17453713%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference