(Q28301018)

1

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Gregory S Harms

2

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Mirko Hekman

3

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Christiaan Karreman

4

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Tripat Kaur Oberoi

5

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Emad S Alnemri

6

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Ulf R Rapp

7

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Krishnaraj Rajalingam

Human inhibitor of apoptosis proteins: why XIAP is the black sheep of the family

8

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language of work or name

English

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publication date

December 2008

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published in

Nature Cell Biology

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volume

10

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page(s)

1447-55

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issue

12

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cites work

1 reference

A novel role for XIAP in copper homeostasis through regulation of MURR1

21 April 2017

1 reference

Regulation of cell motility by mitogen-activated protein kinase

21 April 2017

1 reference

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis

21 April 2017

1 reference

Cooperation of a ubiquitin domain protein and an E3 ubiquitin ligase during chaperone/proteasome coupling

21 April 2017

1 reference

Targeting RAS signalling pathways in cancer therapy

21 April 2017

1 reference

IAP proteins: blocking the road to death's door

21 April 2017

1 reference

The RAF proteins take centre stage

21 April 2017

1 reference

MAP kinase signalling pathways in cancer

21 April 2017

1 reference

Pathways of chaperone-mediated protein folding in the cytosol

21 April 2017

1 reference

Ras oncogenes and their downstream targets

21 April 2017

1 reference

7 January 2021

IAPs: what's in a name?

1 reference

7 January 2021

Reawakening the cellular death program in neoplasia through the therapeutic blockade of IAP function

1 reference

7 January 2021

IAPs, RINGs and ubiquitylation

1 reference

7 January 2021

XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland.

1 reference

7 January 2021

Role of Raf in vascular protection from distinct apoptotic stimuli

1 reference

7 January 2021

Bcl-2 proteins: master switches at the intersection of death signaling and the survival control by Raf kinases

1 reference

7 January 2021

Prohibitin is required for Ras-induced Raf-MEK-ERK activation and epithelial cell migration

1 reference

7 January 2021

Targeting IAP (inhibitor of apoptosis) proteins for therapeutic intervention in tumors

1 reference

7 January 2021

Activated B-RAF is an Hsp90 client protein that is targeted by the anticancer drug 17-allylamino-17-demethoxygeldanamycin

1 reference

7 January 2021

V600E B-Raf requires the Hsp90 chaperone for stability and is degraded in response to Hsp90 inhibitors

1 reference

7 January 2021

CHIP: a link between the chaperone and proteasome systems

1 reference

7 January 2021

To be, or not to be--molecular chaperones in protein degradation

1 reference

7 January 2021

Heat shock protein 90 as a molecular target for cancer therapeutics

1 reference

7 January 2021

Destabilization of Raf-1 by geldanamycin leads to disruption of the Raf-1-MEK-mitogen-activated protein kinase signalling pathway

1 reference

7 January 2021

Geldanamycin-induced destabilization of Raf-1 involves the proteasome

1 reference

7 January 2021

Pharmacologic shifting of a balance between protein refolding and degradation mediated by Hsp90

1 reference

7 January 2021

CRAF autophosphorylation of serine 621 is required to prevent its proteasome-mediated degradation

1 reference

7 January 2021

Characterization of XIAP-deficient mice

1 reference

7 January 2021

IAP-IAP complexes required for apoptosis resistance of C. trachomatis-infected cells

1 reference

7 January 2021