(Q28303405)

Journal of Biological Chemistry

GOA release 2020-03-11

author name string

Saravanakumar Narayanan

series ordinal

1

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Toru Sato

series ordinal

2

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Michael S Wolfe

series ordinal

3

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language of work or name

English

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publication date

13 July 2007

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published in

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volume

282

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issue

28

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page(s)

20172-9

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cites work

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Electron microscopic structure of purified, active gamma-secretase reveals an aqueous intramembrane chamber and two pores

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Signal peptide peptidase forms a homodimer that is labeled by an active site-directed gamma-secretase inhibitor

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Signal peptide peptidase: biochemical properties and modulation by nonsteroidal antiinflammatory drugs

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Deducing the transmembrane domain organization of presenilin-1 in gamma-secretase by cysteine disulfide cross-linking

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Interaction with telencephalin and the amyloid precursor protein predicts a ring structure for presenilins

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Activity-dependent isolation of the presenilin- gamma -secretase complex reveals nicastrin and a gamma substrate

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Signal peptide peptidase is required for dislocation from the endoplasmic reticulum

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Analysis of Notch function in presomitic mesoderm suggests a gamma-secretase-independent role for presenilins in somite differentiation.

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Presenilins form ER Ca2+ leak channels, a function disrupted by familial Alzheimer's disease-linked mutations

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A presenilin dimer at the core of the gamma-secretase enzyme: insights from parallel analysis of Notch 1 and APP proteolysis

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Three-dimensional structure of the γ-secretase complex

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