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A labile point in mutant amphotericin polyketide synthases

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A labile point in mutant amphotericin polyketide synthases (English)

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author name string

Naseem Khan

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1

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Bernard Rawlings

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2

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Patrick Caffrey

series ordinal

3

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language of work or name

English

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publication date

June 2011

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published in

Biotechnology Letters

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volume

33

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issue

6

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page(s)

1121-6

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cites work

Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes

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21 January 2018

Biosynthetic engineering of polyene macrolides towards generation of improved antifungal and antiparasitic agents.

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Analysis and manipulation of amphotericin biosynthetic genes by means of modified phage KC515 transduction techniques

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21 January 2018

Stereospecificity of ketoreductase domains of the 6-deoxyerythronolide B synthase

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21 January 2018

Biosynthesis of pyrrolylpolyenes in Auxarthron umbrinum.

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21 January 2018

Role of type II thioesterases: evidence for removal of short acyl chains produced by aberrant decarboxylation of chain extender units

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21 January 2018

Complete reconstitution of a highly reducing iterative polyketide synthase

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21 January 2018

2-Pyrone natural products and mimetics: isolation, characterisation and biological activity

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Isolation and characterisation of amphotericin B analogues and truncated polyketide intermediates produced by genetic engineering of Streptomyces nodosus

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Engineered synthesis of 7-oxo- and 15-deoxy-15-oxo-amphotericins: insights into structure-activity relationships in polyene antibiotics

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21 January 2018

Predicting the nature and timing of epimerisation on a modular polyketide synthase.

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21 January 2018

The biochemical basis for stereochemical control in polyketide biosynthesis

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21 January 2018

The Molecular Basis of Celmer's Rules: The Stereochemistry of the Condensation Step in Chain Extension on the Erythromycin Polyketide Synthase†

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21 January 2018

Identifiers

DOI

10.1007/S10529-011-0538-3

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PubMed publication ID

21267757

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ResearchGate publication ID

49786162

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(Q28304029)

A labile point in mutant amphotericin polyketide synthases

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