(Q28316436)

English

Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma

scientific article (publication date: August 1992)

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scholarly article

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Effects of (-)-2'-deoxy-3'-thiacytidine (3TC) 5'-triphosphate on human immunodeficiency virus reverse transcriptase and mammalian DNA polymerases alpha, beta, and gamma (English)

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1 reference

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author name string

G J Hart

1

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D C Orr

2

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C R Penn

3

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H T Figueiredo

4

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N M Gray

5

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R E Boehme

6

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J M Cameron

7

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language of work or name

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publication date

August 1992

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Antimicrobial Agents and Chemotherapy

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36

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8

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1688-94

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Herpes simplex virus type 1 and human DNA polymerase interactions with 2'-deoxyguanosine 5'-triphosphate analogues. Kinetics of incorporation into DNA and induction of inhibition

1 reference

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1 reference

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1 reference

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1 reference

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The separated enantiomers of 2'-deoxy-3'-thiacytidine (BCH 189) both inhibit human immunodeficiency virus replication in vitro

1 reference

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20 March 2017

(-)-2'-deoxy-3'-thiacytidine is a potent, highly selective inhibitor of human immunodeficiency virus type 1 and type 2 replication in vitro

1 reference

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DNA chain termination activity and inhibition of human immunodeficiency virus reverse transcriptase by carbocyclic 2',3'-didehydro-2',3'-dideoxyguanosine triphosphate

1 reference

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DNA sequencing with chain-terminating inhibitors

1 reference

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Preparation and preliminary characterization of monoclonal antibodies against human DNA polymerase alpha.

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DNA polymerases of tumor virus: specific effect of ethidium bromide on the use of different synthetic templates

1 reference

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Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2',3'-dideoxycytidine

1 reference

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Cellular metabolism of 2',3'-dideoxycytidine, a compound active against human immunodeficiency virus in vitro

1 reference

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Cellular metabolism of (−) enantiomeric 2′-deoxy-3′-thiacytidine

1 reference

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Comparison of the effect of Carbovir, AZT, and dideoxynucleoside triphosphates on the activity of human immunodeficiency virus reverse transcriptase and selected human polymerases

1 reference

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27 November 2018

Enzymatic synthesis of deoxyribonucleic acid. IX. The polymerase formed after T2 bacteriophage infection of Escherichia coli: a new enzyme

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Metabolic pathways for the activation of the antiretroviral agent 2',3'-dideoxyadenosine in human lymphoid cells

1 reference

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HeLa cell DNA polymerase gamma: further purification and properties of the enzyme

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Initial studies on the cellular pharmacology of 2',3'-dideoxyinosine, an inhibitor of HIV infectivity

1 reference

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Identifiers

10.1128/AAC.36.8.1688

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