(Q28318388)

Europe PubMed Central

PubMed publication ID

1505142

https://www.ebi.ac.uk/europepmc/webservices/rest/search?resulttype=core&format=json&query=SRC%3AMED%20AND%20EXT_ID%3A1505142

Clinical Pharmacokinetics

3 October 2022

language of work or name

English

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publication date

May 1992

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published in

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volume

22

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issue

5

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page(s)

359-74

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cites work

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Low-molecular-weight heparin and prevention of postoperative deep vein thrombosis

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Treatment of heparin-associated thrombocytopenia and thrombosis with low molecular weight heparin (CY 216).

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Evaluation of an amidolytic heparin assay method: increased sensitivity by adding purified antithrombin III

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Further characterization of the antithrombin-binding sequence in heparin

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Heparin kinetics in venous thrombosis and pulmonary embolism

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A catalytic role for heparin. Evidence for a ternary complex of heparin cofactor thrombin and heparin

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Low molecular weight heparin half life is prolonged in haemodialysed patients

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The antithrombotic activity and pharmacokinetics of enoxaparine, a low molecular weight heparin, in humans given single subcutaneous doses of 20 to 80 mg.

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Heparin pharmacokinetics: increased requirements in pulmonary embolism

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Selective binding of heparins to human endothelial cells. Implications for pharmacokinetics

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Heparin-induced platelet aggregation: dose/response relationships for a low molecular weight heparin derivative (PK 10169) and its subfractions

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Heparin therapy in venous thromboembolism

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Heparin fractions with high and low affinities to antithrombin III are cleared at different rates

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Antithrombotic effects of heparin oligosaccharides

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Decreased binding of heparin to antithrombin following the interaction between antithrombin and thrombin

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Structural studies on a biologically active hexasaccharide obtained from heparin

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Low molecular weight heparin (KABI 2165, Fragmin): pharmacokinetics after intravenous and subcutaneous administration in human volunteers

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Heparin-induced thrombocytopenia, thrombosis, and hemorrhage

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Heparin with low affinity to antithrombin III inhibits the activation of prothrombin in normal plasma.

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Heparin clearance in the newborn

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A heparin-degrading endoglycosidase from rat spleen

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Anticoagulant properties of heparin fractionated by affinity chromatography on matrix-bound antithrombin iii and by gel filtration

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Low molecular weight heparin Novo (LHN-1) does not cross the placenta during the second trimester of pregnancy

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Thrombocytopenia occurring during the administration of heparin. A prospective study in 52 patients

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Pharmacokinetics of fragmin. A comparative study in the rabbit of its high and low affinity forms for antithrombin

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Heparin treatment of deep vein thrombosis. Effects and complications after continuous or intermittent heparin administration

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Kinetics of Heparin Administration

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Relationship between the anticoagulant and antithrombotic effects of heparin in experimental venous thrombosis

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The inhibition by heparin of the intrinsic pathway activation of factor X in the absence of antithrombin-III

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Evaluation of critical groups required for the binding of heparin to antithrombin

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Determination of the biological activity of heparin by use of a chromogenic substrate

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The relationship between the hemorrhagic and antithrombotic properties of low molecular weight heparin in rabbits

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White clot syndrome. Peripheral vascular complications of heparin therapy

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Intersubject variability in the anticoagulant response to heparin in vitro

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Variability in heparin sensitivity of APTT reagents

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Heparin elimination in uraemic patients on Haemodialysis

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Management of heparin therapy: Controlled prospective trial

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Heparin clearance and ex vivo recovery in newborn piglets and adult pigs.

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Increased anti-Xa bioavailability for a low molecular weight heparin (PK 10169) compared with unfractionated heparin

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Endothelial binding sites for heparin. Specificity and role in heparin neutralization

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Evidence for a 3-O-sulfated D-glucosamine residue in the antithrombin-binding sequence of heparin

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Assay of heparin in plasma using a chromogenic substrate for activated factor X

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Inhibition of human factor IXa by human antithrombin

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Heparin-induced thrombocytopenia

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Pharmacokinetics of heparin. II. Studies of time dependence in rats

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Unfractionated heparin and CY 216: pharmacokinetics and bioavailabilities of the antifactor Xa and IIa effects after intravenous and subcutaneous injection in the rabbit

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Relationship between biological activity and concentration of a low-molecular-weight heparin (PK 10169) and unfractionated heparin after intravenous and subcutaneous administration

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Low-affinity heparin potentiates the action of high-affinity heparin oligosaccharides

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Effects of N-deacetylation and N-desulfation of heparin on its anticoagulant activity and in vivo disposition

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The relative importance of thrombin inhibition and factor Xa inhibition to the antithrombotic effects of heparin.

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A Standard Heparin Nomogram for the Management of Heparin Therapy

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Heparin assay methods for control of in vivo heparin effects

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Heparin degradation in the endothelial cells

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12 December 2020

Relationship between the antithrombotic and anticoagulant effects of low molecular weight heparin

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12 December 2020

Pharmacokinetics of heparin and low molecular weight heparin fragment (Fragmin) in rabbits with impaired renal or metabolic clearance

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12 December 2020

Preventive and therapeutic approach to venous thromboembolic disease and pulmonary embolism--can death from pulmonary embolism be prevented?

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12 December 2020

Selective distribution of the heparin in mammals: conspicuous presence of heparin in lymphoid tissues

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Placental transport of heparin

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12 December 2020

Heparin therapy: a randomized prospective study

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12 December 2020

Effects of heparin oligosaccharides with high affinity for antithrombin III in experimental venous thrombosis

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12 December 2020

Actions and Interactions of Antithrombin and Heparin

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12 December 2020

Heparin-associated thrombocytopenia treatment with low molecular weight heparin.

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The comparison of the pharmacokinetics of a low molecular weight heparin in the newborn and adult pig.

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12 December 2020