(Q28322430)

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Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine

scientific article (publication date: 10 June 1979)

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Coordinate overproduction of orotate phosphoribosyltransferase and orotidine-5'-phosphate decarboxylase in hamster cells resistant to pyrazofurin and 6-azauridine (English)

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10.1016/S0021-9258(17)30053-4

https://api.crossref.org/works/10.1016/S0021-9258(17)30053-4

15 January 2023

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10.1016/S0021-9258(17)30053-4

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D. P. Suttle

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Europe PubMed Central

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15 January 2023

G. R. Stark

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Europe PubMed Central

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publication date

10 June 1979

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http://intl.jbc.org/cgi/content/abstract/254/11/4602

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Europe PubMed Central

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15 January 2023

https://api.elsevier.com/content/article/PII:S0021925817300534?httpAccept=text/xml

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10.1016/S0021-9258(17)30053-4

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https://api.elsevier.com/content/article/PII:S0021925817300534?httpAccept=text/plain

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Journal of Biological Chemistry

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254

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4602-7

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11

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describes a project that uses

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Uridylic acid synthesis in Ehrlich ascites carcinoma. Properties, subcellular distribution, and nature of enzyme complexes of the six biosynthetic enzymes

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The cellular location of dihydroorotate dehydrogenase: Relation to de novo biosynthesis of pyrimidines

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15 January 2023

Cancer Research

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38

371

author name string

Johnson

publication date

1978

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10.1016/S0021-9258(17)30053-4

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Stable mutants of mammalian cells that overproduce the first three enzymes of pyrimidine nucleotide biosynthesis

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Cancer Research

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4382

author name string

Janeway

publication date

1977

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Cancer Research

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33

2619

author name string

Sweeney

publication date

1973

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10.1016/S0021-9258(17)30053-4

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Biochemistry and biological effects of the pyrazofurins (pyrazomycins): initial clinical trial

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3807

author name string

Plagemann

publication date

1976

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10.1016/S0021-9258(17)30053-4

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Cancer Research

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author name string

Cadman

publication date

1978

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The transformation of BHK 21 hamster cells by simian virus 40.

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The rapid separation of orotate, orotidylate, and uridylate by thin-layer chromatography. Utility in the assay of orotate phosphoribosyltransferase and orotidylate decarboxylase

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Protein measurement with the Folin phenol reagent

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Possible Enzymic Mechanism for the Development of Resistance against Fluorouracil in Ascites Tumours

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Studies on the control of pyrimidine biosynthesis in human diploid cell strains, I. Effect of 6-azauridine on cellular phenotype

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Hereditary Orotic Aciduria: Evidence for a Structural Gene Mutation

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Studies on the coordinate activity and liability of orotidylate phosphoribosyltransferase and decarboxylase in human erythrocytes, and the effects of allopurinol administration

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Mechanism of allopurinol-mediated increase in enzyme activity in man.

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Effect of allopurinol and its metabolic derivatives on the configuration of human orotate phosphoribosyltransferase and orotidine 5'-phosphate decarboxylase

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Orotic aciduria. Differing enzyme patterns

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Subunit structure of the orotate phosphoribosyltransferase--orotidylate decarboxylase complex from human erythrocytes

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1961

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Concurrent development of resistance to 6-azauridine and adenosine in a mouse cell line

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