(Q28343171)

English

Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir

scientific article (publication date: March 1999)

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scholarly article

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Comparative study of the anti-human cytomegalovirus activities and toxicities of a tetrahydrofuran phosphonate analogue of guanosine and cidofovir (English)

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Cytomegalovirus

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author name string

J Bedard

1

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S May

2

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M Lis

3

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L Tryphonas

4

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J Drach

5

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J Huffman

6

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R Sidwell

7

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L Chan

8

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T Bowlin

9

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R Rando

10

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language of work or name

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publication date

March 1999

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Antimicrobial Agents and Chemotherapy

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43

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3

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557-67

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Resistance of human cytomegalovirus to benzimidazole ribonucleosides maps to two open reading frames: UL89 and UL56

1 reference

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20 March 2017

1-[((S)-2-hydroxy-2-oxo-1,4,2-dioxaphosphorinan-5-yl)methyl] cytosine, an intracellular prodrug for (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine with improved therapeutic index in vivo

1 reference

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20 March 2017

Inhibitory effects of acyclic nucleoside phosphonates on human hepatitis B virus and duck hepatitis B virus infections in tissue culture

1 reference

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20 March 2017

Inhibition of human cytomegalovirus in culture by alkenyl guanine analogs of the thiazolo[4,5-d]pyrimidine ring system

1 reference

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20 March 2017

Selective inhibitory effect of (S)-9-(3-hydroxy-2-phosphonylmethoxypropyl)adenine and 2'-nor-cyclic GMP on adenovirus replication in vitro

1 reference

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20 March 2017

Inhibitory effects of selected antiviral compounds on human hepatitis B virus DNA synthesis

1 reference

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20 March 2017

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1 reference

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20 March 2017

Synthesis and antiviral activity of methyl derivatives of 9-[2-(phosphonomethoxy)ethyl]guanine

1 reference

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Altered natural history of AIDS-related opportunistic infections in the era of potent combination antiretroviral therapy

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29 September 2017

Design, synthesis, and antiviral evaluation of 2-substituted 4,5-dichloro- and 4,6-dichloro-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections

1 reference

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29 September 2017

Single amino acid changes in the DNA polymerase confer foscarnet resistance and slow-growth phenotype, while mutations in the UL97-encoded phosphotransferase confer ganciclovir resistance in three double-resistant human cytomegalovirus strains recov

1 reference

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29 September 2017

Double resistance to ganciclovir and foscarnet of four human cytomegalovirus strains recovered from AIDS patients

1 reference

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29 September 2017

A point mutation in the human cytomegalovirus DNA polymerase gene confers resistance to ganciclovir and phosphonylmethoxyalkyl derivatives

1 reference

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29 September 2017

Anticytomegaloviral activity and safety of cidofovir in patients with human immunodeficiency virus infection and cytomegalovirus viruria

1 reference

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29 September 2017

Molecular mechanisms of antiviral resistance

1 reference

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29 September 2017

Use of disposable micro tissue culture plates for antiviral and interferon induction studies

1 reference

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A novel selective broad-spectrum anti-DNA virus agent

1 reference

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29 September 2017

Infection in bone marrow transplant recipients

1 reference

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29 September 2017

Pharmacokinetics, safety and preliminary clinical experiences using foscarnet in the treatment of cytomegalovirus infections in bone marrow and renal transplant recipients

1 reference

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29 September 2017

A three-dimensional model to analyze drug-drug interactions

1 reference

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29 September 2017

Ganciclovir-resistant cytomegalovirus clinical isolates: mode of resistance to ganciclovir

1 reference

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29 September 2017

Ganciclovir-resistant human cytomegalovirus clinical isolates; resistance mechanisms and in vitro susceptibility to antiviral agents

1 reference

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29 September 2017

Treatment of cytomegalovirus retinitis in patients with the acquired immunodeficiency syndrome

1 reference

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2 June 2018

High-level resistance of cytomegalovirus to ganciclovir is associated with alterations in both the UL97 and DNA polymerase genes

1 reference

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Selective inhibition of cytomegaloviruses by 9-(3'-ethylphosphono-1'-hydroxymethyl-1'-propyloxy-methyl)g uanine

1 reference

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Activity of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine (HPMPC) against guinea pig cytomegalovirus infection in cultured cells and in guinea pigs

1 reference

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2 June 2018

Risk of developing cytomegalovirus retinitis in persons infected with the human immunodeficiency virus

1 reference

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2 June 2018

A ganciclovir-resistant clinical isolate of human cytomegalovirus exhibiting cross-resistance to other DNA polymerase inhibitors.

1 reference

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Intracellular metabolism of the antiherpes agent (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine

1 reference

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Guidelines for the treatment of cytomegalovirus diseases in patients with AIDS in the era of potent antiretroviral therapy: recommendations of an international panel. International AIDS Society-USA.

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Cytomegalovirus retinitis after initiation of highly active antiretroviral therapy

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Pharmacokinetics, bioavailability, metabolism, and tissue distribution of cidofovir (HPMPC) and cyclic HPMPC in rats

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27 November 2018

Analysis of the UL97 phosphotransferase coding sequence in clinical cytomegalovirus isolates and identification of mutations conferring ganciclovir resistance.

1 reference

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Treatment of anogenital papillomavirus infections with an acyclic nucleoside phosphonate analogue

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27 November 2018

A Randomized, Controlled Trial of Foscarnet in the Treatment of Cytomegalovirus Retinitis in Patients with AIDS

1 reference

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inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

Topical HPMPC inhibits adenovirus type 5 in the New Zealand rabbit ocular replication model

1 reference

https://pubmed.ncbi.nlm.nih.gov/10049267

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10049267

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10049267

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10049267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10049267

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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