(Q28343322)

5 July 2017

title

Human immunodeficiency virus type 1 integrase: arrangement of protein domains in active cDNA complexes (English)

1 reference

5 July 2017

K Gao

1

1 reference

5 July 2017

S L Butler

series ordinal

2

1 reference

5 July 2017

F Bushman

series ordinal

3

1 reference

5 July 2017

language of work or name

English

0 references

publication date

1 July 2001

1 reference

5 July 2017

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5 July 2017

volume

20

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5 July 2017

issue

13

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5 July 2017

page(s)

3565-3576

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Crystal structure of the HIV-1 integrase catalytic core and C-terminal domains: A model for viral DNA binding

5 July 2017

cites work

1 reference

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Three-dimensional structure of the Tn5 synaptic complex transposition intermediate

20 March 2017

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Crystal structure of an active two-domain derivative of Rous sarcoma virus integrase

20 March 2017

1 reference

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X-ray structure of simian immunodeficiency virus integrase containing the core and C-terminal domain (residues 50-293)--an initial glance of the viral DNA binding platform

20 March 2017

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Inhibitors of strand transfer that prevent integration and inhibit HIV-1 replication in cells

20 March 2017

1 reference

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The mobility of an HIV-1 integrase active site loop is correlated with catalytic activity

20 March 2017

1 reference

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Isolation and characterization of novel human immunodeficiency virus integrase inhibitors from fungal metabolites

20 March 2017

1 reference

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Structure of a covalently trapped catalytic complex of HIV-1 reverse transcriptase: implications for drug resistance

20 March 2017

1 reference

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Crystal structures of the catalytic domain of HIV-1 integrase free and complexed with its metal cofactor: high level of similarity of the active site with other viral integrases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules

20 March 2017

1 reference

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Solution structure of the DNA binding domain of HIV-1 integrase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

High-resolution structure of the catalytic domain of avian sarcoma virus integrase

20 March 2017

1 reference

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Retroviral DNA integration directed by HIV integration protein in vitro

20 March 2017

1 reference

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Repair of gaps in retroviral DNA integration intermediates

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Trans catalysis in Tn5 transposition

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Structural determinants of metal-induced conformational changes in HIV-1 integrase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Sequence specificity of viral end DNA binding by HIV-1 integrase reveals critical regions for protein-DNA interaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Effects of mutations in residues near the active site of human immunodeficiency virus type 1 integrase on specific enzyme-substrate interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Structure-based mutational analysis of the C-terminal DNA-binding domain of human immunodeficiency virus type 1 integrase: critical residues for protein oligomerization and DNA binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Modifying the helical structure of DNA by design: recruitment of an architecture-specific protein to an enforced DNA bend.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Critical contacts between HIV-1 integrase and viral DNA identified by structure-based analysis and photo-crosslinking

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Identification of discrete functional domains of HIV-1 integrase and their organization within an active multimeric complex

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Complementation between HIV integrase proteins mutated in different domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

A stable complex between integrase and viral DNA ends mediates human immunodeficiency virus integration in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

DNA bending creates favored sites for retroviral integration: an explanation for preferred insertion sites in nucleosomes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Efficient magnesium-dependent human immunodeficiency virus type 1 integrase activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

The DNA-binding domain of HIV-1 integrase has an SH3-like fold

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

In vitro integration of human immunodeficiency virus type 1 cDNA into targets containing protein-induced bends

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

The avian retroviral integration protein cleaves the terminal sequences of linear viral DNA at the in vivo sites of integration

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Human immunodeficiency virus integration protein expressed in Escherichia coli possesses selective DNA cleaving activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Substrate specificity of recombinant human immunodeficiency virus integrase protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Concerted integration of viral DNA termini by purified avian myeloblastosis virus integrase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Nucleosomes, DNA-binding proteins, and DNA sequence modulate retroviral integration target site selection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

The IN protein of Moloney murine leukemia virus processes the viral DNA ends and accomplishes their integration in vitro

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

The avian retroviral IN protein is both necessary and sufficient for integrative recombination in vitro.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Trapping of a catalytic HIV reverse transcriptase*template:primer complex through a disulfide bond.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Mapping features of HIV-1 integrase near selected sites on viral and target DNA molecules in an active enzyme-DNA complex by photo-cross-linking.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

Target DNA capture by HIV-1 integration complexes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=125503

HIV-1 DNA integration: Mechanism of viral DNA cleavage and DNA strand transfer

27 November 2018

1 reference

12 December 2020

The interwoven architecture of the Mu transposase couples DNA synapsis to catalysis

1 reference

12 December 2020

Mu transpositional recombination: donor DNA cleavage and strand transfer in trans by the Mu transposase

1 reference

12 December 2020

The solution structure of the amino-terminal HHCC domain of HIV-2 integrase: a three-helix bundle stabilized by zinc

1 reference

12 December 2020

Retroviral cDNA integration: mechanism, applications and inhibition

1 reference

12 December 2020

Identifiers

DOI

10.1093/EMBOJ/20.13.3565

1 reference

5 July 2017

1 reference

5 July 2017

1 reference