(Q28344995)

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Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

atherosclerosis

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S L Hazen

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J P Gaut

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J R Crowley

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

F F Hsu

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

J W Heinecke

5

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Europe PubMed Central

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2 November 2019

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publication date

1 December 2000

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Europe PubMed Central

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2 November 2019

Biochemical Journal

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

352 Pt 3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

693-699

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

20 March 2017

Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

20 March 2017

Evidence for a dominant role of lipoxygenase(s) in the oxidation of LDL by mouse peritoneal macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

20 March 2017

Studies on the chlorinating activity of myeloperoxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

20 March 2017

A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

7 April 2017

Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

7 April 2017

The myeloperoxidase system of human phagocytes generates Nepsilon-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Mass spectrometric quantification of amino acid oxidation products in proteins: insights into pathways that promote LDL oxidation in the human artery wall

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Modification of type III VLDL, their remnants, and VLDL from ApoE-knockout mice by p-hydroxyphenylacetaldehyde, a product of myeloperoxidase activity, causes marked cholesteryl ester accumulation in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Protein-bound acrolein: potential markers for oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsatu

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

The role of oxidized lipoproteins in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Presence of hypochlorite-modified proteins in human atherosclerotic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Iron and copper promote modification of low density lipoprotein by human arterial smooth muscle cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Role of oxidized low density lipoprotein in atherogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Differential inactivation of Escherichia coli membrane dehydrogenases by a myeloperoxidase-mediated antimicrobial system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

The role of lipid peroxidation and antioxidants in oxidative modification of LDL.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

29 September 2017

Vitamin C protects against and reverses specific hypochlorous acid- and chloramine-dependent modifications of low-density lipoprotein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Human neutrophils employ myeloperoxidase to convert alpha-amino acids to a battery of reactive aldehydes: a pathway for aldehyde generation at sites of inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Formation of o-tyrosine and dityrosine in proteins during radiolytic and metal-catalyzed oxidation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Extensive nitration of protein tyrosines in human atherosclerosis detected by immunohistochemistry

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Brominating oxidants generated by human eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Recognition of oxidized low density lipoprotein by the scavenger receptor of macrophages results from derivatization of apolipoprotein B by products of fatty acid peroxidation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Distribution of oxidation specific lipid-protein adducts and apolipoprotein B in atherosclerotic lesions of varying severity from WHHL rabbits

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

2 June 2018

Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

27 November 2018

Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221506

27 November 2018

Coexistence of oxidized lipids and alpha-tocopherol in all lipoprotein density fractions isolated from advanced human atherosclerotic plaques

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Scavenger receptor-independent stimulation of cholesterol esterification in macrophages by low density lipoprotein extracted from human aortic intima

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes. A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Vitamin E supplementation and cardiovascular events in high-risk patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enthalpy of decomposition of hydrogen peroxide by catalase at 25° C (with molar extinction coefficients of H2O2 solutions in the UV)

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystallization and properties of myeloperoxidase from normal human leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxidation of human low density lipoprotein results in derivatization of lysine residues of apolipoprotein B by lipid peroxide decomposition products

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of sulfur-containing amino acids in superoxide production and modification of low density lipoprotein by arterial smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of low density lipoprotein from atherosclerotic vascular tissue of Watanabe heritable hyperlipidemic rabbits

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

p-Hydroxyphenylacetaldehyde, the major product of L-tyrosine oxidation by the myeloperoxidase-H2O2-chloride system of phagocytes, covalently modifies epsilon-amino groups of protein lysine residues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of oxidative stress in diabetic complications: a new perspective on an old paradigm

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modification of proteins and lipids by myeloperoxidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detecting oxidative modification of biomolecules with isotope dilution mass spectrometry: sensitive and quantitative assays for oxidized amino acids in proteins and tissues

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Peroxidases and human disease: a meeting of minds. The peroxidase multigene family of enzymes: biochemical basis and clinical applications. Fraueninsel, Germany, 27 September-2 October 1998

1 reference

https://pubmed.ncbi.nlm.nih.gov/11104675

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3520693

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11104675%20AND%20SRC:MED&resulttype=core&format=json

2 November 2019

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