(Q28347638)

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A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

A thiol proteinase inhibitor, E-64-d, corrects the abnormalities in concanavalin A cap formation and the lysosomal enzyme activity in leucocytes from patients with Chediak-Higashi syndrome by reversing the down-regulated protein kinase C activity (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Chediak-Higashi syndrome

1 reference

based on heuristic

inferred from title

protein kinase C activity

1 reference

based on heuristic

inferred from title

Yasumasa Iwatani

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

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S H Cui

1

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10 November 2019

F Tanabe

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

H Terunuma

3

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10 November 2019

H Nunoi

5

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10 November 2019

K Agematsu

6

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

A Komiyama

7

1 reference

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

A Nomura

8

1 reference

Europe PubMed Central

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10 November 2019

T Hara

9

1 reference

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10 November 2019

T Onodera

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

T Iwata

11

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

M Ito

12

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10 November 2019

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1 August 2001

1 reference

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10 November 2019

Clinical and Experimental Immunology

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

125

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10 November 2019

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

283-290

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

Protein truncation test of LYST reveals heterogenous mutations in patients with Chediak-Higashi syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

20 March 2017

Deficient peptide loading and MHC class II endosomal sorting in a human genetic immunodeficiency disease: the Chediak-Higashi syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

20 March 2017

Defective lysosomal enzyme secretion in kidneys of Chediak-Higashi (beige) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

20 March 2017

Congenital gigantism of peroxidase granules; the first case ever reported of qualitative abnormity of peroxidase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Genetic and physical mapping of the Chediak-Higashi syndrome on chromosome 1q42-43.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Identification of the homologous beige and Chediak-Higashi syndrome genes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Leukocyte elastase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Capping and the Cytoskeleton

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Turnover of Inositol Phospholipids and Signal Transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Lysosomal elastase and cathepsin G in beige mice. Neutrophils of beige (Chediak-Higashi) mice selectively lack lysosomal elastase and cathepsin G.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Studies and perspectives of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Specific protease deficiency in polymorphonuclear leukocytes of Chédiak-Higashi syndrome and beige mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

A new and highly sensitive fluorescence assay for collagenase-like peptidase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Cell biology of leukocyte abnormalities--membrane and cytoskeletal function in normal and defective cells. A review

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Role of microtubules in granulocyte adherence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Concanavalin A cap formation on polymorphonuclear leukocytes of normal and beige (Chediak-Higashi) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

29 September 2017

Identification and mutation analysis of the complete gene for Chediak-Higashi syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

2 June 2018

Identification of the murine beige gene by YAC complementation and positional cloning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

2 June 2018

Processing and intracellular transport of cathepsin G and neutrophil elastase in the leukemic myeloid cell line U-937-modulation by brefeldin A, ammonium chloride, and monensin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

2 June 2018

Evidence that ceramide selectively inhibits protein kinase C-alpha translocation and modulates bradykinin activation of phospholipase D.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

2 June 2018

Chelerythrine is a potent and specific inhibitor of protein kinase C.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1906125

2 June 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2001.01598.X

21 January 2018

A new immunodeficiency disorder in humans involving NK cells

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2001.01598.X

21 January 2018

Phorbol esters increase the amount of Ca2+, phospholipid-dependent protein kinase associated with plasma membrane

1 reference

https://api.crossref.org/works/10.1046%2FJ.1365-2249.2001.01598.X

21 January 2018

Reaction of Calcium-Activated Neutral Protease (CANP) with an Epoxysuccinyl Derivative (E64c) and Iodoacetic Acid1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thiol proteinase inhibitors reverse the increased protein kinase C down-regulation and concanavalin A cap formation in polymorphonuclear leukocytes from Chediak-Higashi syndrome (beige) mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Differential inhibition of calpain and proteasome activities by peptidyl aldehydes of di-leucine and tri-leucine

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid down-regulation of protein kinase C in (Chediak-Higashi syndrome) beige mouse by phorbol ester

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms of human cell-mediated cytotoxicity. II. Correction of the selective defect in natural killing in the Chediak-Higashi syndrome with inducers of intracellular cyclic GMP

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ceramide promotes calpain-mediated proteolysis of protein kinase C beta in murine polymorphonuclear leukocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Programmed cell death induced by ceramide

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Sphingomyelin turnover induced by vitamin D3 in HL-60 cells. Role in cell differentiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Possible involvement of microfilaments in protein kinase C translocation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[New leukocyte anomaly of constitutional and familial character]

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chediak-Higashi lymphoblastoid cell lines: granule characteristics and expression of lysosome-associated membrane proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The thiol proteinase inhibitors improve the abnormal rapid down-regulation of protein kinase C and the impaired natural killer cell activity in (Chediak-Higashi syndrome) beige mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormal down-regulation of PKC is responsible for giant granule formation in fibroblasts from CHS (beige) mice--a thiol proteinase inhibitor, E-64-d, prevents giant granule formation in beige fibroblasts

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alteration of Sphingolipid Metabolism in Leukocytes from Patients with the Chediak–Higashi Syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neutrophils in beige mice secrete normal amounts of cathepsin G and a 46 kDa latent form of elastase that can be activated extracellularly by proteolytic activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro and in vivo inhibition of cysteine proteinases by EST, a new analog of E-64

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11529921

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1046/J.1365-2249.2001.01598.X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

PMC publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11529921%20AND%20SRC:MED&resulttype=core&format=json

10 November 2019

ResearchGate publication ID

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