(Q28360158)

English

Dual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonists

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scholarly article

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Dual effects of muscarinic M(2) acetylcholine receptors on the synthesis of cyclic AMP in CHO cells: dependence on time, receptor density and receptor agonists (English)

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1 reference

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author name string

P Michal

1

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M Lysíková

2

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S Tucek

3

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language of work or name

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publication date

March 2001

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British Journal of Pharmacology

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132

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6

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1217-28

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Evidence for a tandem two-site model of ligand binding to muscarinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

20 March 2017

Muscarinic m1 receptor-stimulated adenylate cyclase activity in Chinese hamster ovary cells is mediated by Gs alpha and is not a consequence of phosphoinositidase C activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

20 March 2017

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

20 March 2017

G-protein coupled receptors: conformations and states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

The stability of the agonist beta2-adrenergic receptor-Gs complex: evidence for agonist-specific states

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

The second intracellular loop of the alpha2-adrenergic receptors determines subtype-specific coupling to cAMP production

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Differential effects of the M1-M5 muscarinic acetylcholine receptor subtypes on intracellular calcium and on the incorporation of choline into membrane lipids in genetically modified Chinese hamster ovary cell lines

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Activation of muscarinic acetylcholine receptors via their allosteric binding sites.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Constitutive activation of a single effector pathway: evidence for multiple activation states of a G protein-coupled receptor.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Membrane organization in G-protein mechanisms.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Muscarinic receptors--characterization, coupling and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Cloning, sequence analysis, and permanent expression of a human alpha 2-adrenergic receptor in Chinese hamster ovary cells. Evidence for independent pathways of receptor coupling to adenylate cyclase attenuation and activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Promiscuous or heterogeneous muscarinic receptors in rat atria? I. Schild analysis with simple competitive antagonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

29 September 2017

Activation of adenylate cyclase by human recombinant sst5 receptors expressed in CHO-K1 cells and involvement of Galphas proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Positive cooperativity of acetylcholine and other agonists with allosteric ligands on muscarinic acetylcholine receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Differential regulation of cAMP-mediated gene transcription by m1 and m4 muscarinic acetylcholine receptors. Preferential coupling of m4 receptors to Gi alpha-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Muscarinic agonist-induced positive inotropic response in chick atria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Positive inotropic effects induced by carbachol in rat atria treated with islet-activating protein (IAP) - association with phosphatidylinositol breakdown

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Negative and positive inotropic responses to muscarinic agonists in guinea pig and rat atria in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Antagonist binding properties of five cloned muscarinic receptors expressed in CHO-K1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Functional responses of cloned muscarinic receptors expressed in CHO-K1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

2 June 2018

Dual activation and inhibition of adenylyl cyclase by cannabinoid receptor agonists: evidence for agonist-specific trafficking of intracellular responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572666

27 November 2018

Simultaneous coupling of alpha 2-adrenergic receptors to two G-proteins with opposing effects. Subtype-selective coupling of alpha 2C10, alpha 2C4, and alpha 2C2 adrenergic receptors to Gi and Gs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective coupling of alpha 2-adrenergic receptor subtypes to cyclic AMP-dependent reporter gene expression in transiently transfected JEG-3 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A novel mechanism for coupling of m4 muscarinic acetylcholine receptors to calmodulin-sensitive adenylyl cyclases: crossover from G protein-coupled inhibition to stimulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Contribution of ligand structure to activation of alpha 2-adrenergic receptor subtype coupling to Gs

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Discrete activation of transduction pathways associated with acetylcholine m1 receptor by several muscarinic ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of adenylyl cyclase catalytic activity using single and double column procedures

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Porcine m2 muscarinic acetylcholine receptor-effector coupling in Chinese hamster ovary cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Subtype selectivity of the positive allosteric action of alcuronium at cloned M1-M5 muscarinic acetylcholine receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a Gs coupling domain in the amino terminus of the third intracellular loop of the alpha 2A-adrenergic receptor. Evidence for distinct structural determinants that confer Gs versus Gi coupling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of activation of Gs but not Gi following expression of an alpha2A-adrenoceptor-Gi1alpha fusion protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clozapine interaction with the M2 and M4 subtypes of muscarinic receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11250872

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0703931

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