(Q28363236)

English

Phosphate-binding loop and Rab GTPase function: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype

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scholarly article

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Phosphate-binding loop and Rab GTPase function: mutations at Ser29 and Ala30 of Rab5 lead to loss-of-function as well as gain-of-function phenotype (English)

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author name string

G Li

1

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Z Liang

2

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language of work or name

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publication date

1 May 2001

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Biochemical Journal

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355

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Pt 3

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681-9

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Oligomeric complexes link Rab5 effectors with NSF and drive membrane fusion via interactions between EEA1 and syntaxin 13

1 reference

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20 March 2017

Structural basis of activation and GTP hydrolysis in Rab proteins

1 reference

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1 reference

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20 March 2017

The tuberous sclerosis 2 gene product, tuberin, functions as a Rab5 GTPase activating protein (GAP) in modulating endocytosis

1 reference

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20 March 2017

The human Rab genes encode a family of GTP-binding proteins related to yeast YPT1 and SEC4 products involved in secretion

1 reference

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20 March 2017

Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

1 reference

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20 March 2017

Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

1 reference

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20 March 2017

The GTPase superfamily: a conserved switch for diverse cell functions

1 reference

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20 March 2017

Binding and hydrolysis of guanine nucleotides by Sec4p, a yeast protein involved in the regulation of vesicular traffic.

1 reference

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20 March 2017

Rab geranylgeranyl transferase. A multisubunit enzyme that prenylates GTP-binding proteins terminating in Cys-X-Cys or Cys-Cys

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

20 March 2017

1 reference

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7 April 2017

ras oncogenes in human cancer: a review

1 reference

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7 April 2017

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

7 April 2017

The diversity of Rab proteins in vesicle transport

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

7 April 2017

Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

7 April 2017

rab5 controls early endosome fusion in vitro

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

7 April 2017

The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

7 April 2017

Rab5 induces Rac-independent lamellipodia formation and cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

Rho and Rab small G proteins coordinately reorganize stress fibers and focal adhesions in MDCK cells

1 reference

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Alphavirus-based expression vectors: strategies and applications

1 reference

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29 September 2017

Influence of Mg2+ on the structure and function of Rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

Function and regulation of ras.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

Structural features of the GTP-binding defective Rab5 mutants required for their inhibitory activity on endocytosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

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GTPases: multifunctional molecular switches regulating vesicular traffic

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

Biochemical and functional characterization of a recombinant GTPase, Rab5, and two of its mutants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

29 September 2017

Amino acid residues in the Ras-like GTPase Rab3A that specify sensitivity to factors that regulate the GTP/GDP cycling of Rab3A.

1 reference

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29 September 2017

GTPase mechanism and function: new insights from systematic mutational analysis of the phosphate-binding loop residue Ala30 of Rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

2 June 2018

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1 reference

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2 June 2018

Structure-function relationship of the small GTPase rab5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

2 June 2018

Biological properties of human c-Ha-ras1 genes mutated at codon 12.

1 reference

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2 June 2018

Molecules in the ARF orbit

1 reference

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27 November 2018

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1 reference

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27 November 2018

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1 reference

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27 November 2018

Rab5, an early acting endosomal GTPase, supports in vitro endosome fusion without GTP hydrolysis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221783

27 November 2018

An efficient site-directed mutagenesis method based on PCR

1 reference

https://pubmed.ncbi.nlm.nih.gov/11311130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Catalytic domain of the p120 Ras GAP binds to RAb5 and stimulates its GTPase activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/11311130

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3550681

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