(Q28363755)

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Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

Impairment of myocardial contractility by anticancer anthracyclines: role of secondary alcohol metabolites and evidence of reduced toxicity by a novel disaccharide analogue (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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Pierantonio Menna

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

author name string

G Minotti

1

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3 December 2019

M Parlani

2

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3 December 2019

E Salvatorelli

3

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Europe PubMed Central

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3 December 2019

A Cipollone

5

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3 December 2019

F Animati

6

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3 December 2019

C A Maggi

7

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3 December 2019

S Manzini

8

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3 December 2019

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publication date

1 November 2001

1 reference

Europe PubMed Central

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3 December 2019

British Journal of Pharmacology

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3 December 2019

134

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3 December 2019

6

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Europe PubMed Central

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3 December 2019

1271-1278

1 reference

Europe PubMed Central

PMC publication ID

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3 December 2019

Comparison of doxorubicin- and MEN 10755-induced long-term progressive cardiotoxicity in the rat

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

20 March 2017

The anthracyclines: will we ever find a better doxorubicin?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

20 March 2017

Human carbonyl reductase overexpression in the heart advances the development of doxorubicin-induced cardiotoxicity in transgenic mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Effect of MEN 10755, a new disaccharide analogue of doxorubicin, on sarcoplasmic reticulum Ca(2+) handling and contractile function in rat heart.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Flavonoids as antioxidants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Effect of barbiturates on hydroxyl radicals, lipid peroxidation, and hypoxic cell death in human NT2-N neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Development of daunorubicin resistance in tumour cells by induction of carbonyl reduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Doxorubicin disaccharide analogue: apoptosis-related improvement of efficacy in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Paradoxical inhibition of cardiac lipid peroxidation in cancer patients treated with doxorubicin. Pharmacologic and molecular reappraisal of anthracycline cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Time-related increases in cardiac concentrations of doxorubicinol could interact with doxorubicin to depress myocardial contractile function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Cytokines, iron homeostasis, and cancer.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Secondary alcohol metabolites mediate iron delocalization in cytosolic fractions of myocardial biopsies exposed to anticancer anthracyclines. Novel linkage between anthracycline metabolism and iron-induced cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Monohydroxyethylrutoside as protector against chronic doxorubicin-induced cardiotoxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Doxorubicin cardiotoxicity: analysis of prevailing hypotheses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Anthracyclines and their C-13 alcohol metabolites: growth inhibition and DNA damage following incubation with human tumor cells in culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

29 September 2017

Inhibition of aldo-keto reductases by phenobarbital alters metabolism, pharmacokinetics and toxicity of doxorubicin in rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

2 June 2018

Doxorubicin: mechanism of cardiodepressant actions in guinea pigs

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

2 June 2018

Improved efficacy and enlarged spectrum of activity of a novel anthracycline disaccharide analogue of doxorubicin against human tumor xenografts.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

27 November 2018

Protection against daunorubicin cytotoxicity by expression of a cloned human carbonyl reductase cDNA in K562 leukemia cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1573059

27 November 2018

Role of iron in anthracycline cardiotoxicity: new tunes for an old song?

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anthracycline metabolism and toxicity in human myocardium: comparisons between doxorubicin, epirubicin, and a novel disaccharide analogue with a reduced level of formation and [4Fe-4S] reactivity of its secondary alcohol metabolite

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tissue distribution, antitumour activity and in vivo apoptosis induction by MEN10755 in nude mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Superoxide anion production by adriamycinol from cardiac sarcosomes and by mitochondrial NADH dehydrogenase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytofluorescence localization and disposition of doxorubicin and doxorubicinol in rat cardiac tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of cardiac actions of doxorubicin, pirarubicin and aclarubicin in isolated guinea-pig heart

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein-1 in cytosolic fractions from human myocardium

1 reference

https://pubmed.ncbi.nlm.nih.gov/11704647

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704369

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11704647%20AND%20SRC:MED&resulttype=core&format=json

3 December 2019

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