(Q28365260)

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Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway

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Mutant epidermal growth factor receptor enhances induction of vascular endothelial growth factor by hypoxia and insulin-like growth factor-1 via a PI3 kinase dependent pathway (English)

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author name string

K Clarke

1

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K Smith

2

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W J Gullick

3

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A L Harris

4

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publication date

18 May 2001

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British Journal of Cancer

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84

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10

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1322-9

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Vascular endothelial growth factor regulates endothelial cell survival through the phosphatidylinositol 3'-kinase/Akt signal transduction pathway. Requirement for Flk-1/KDR activation

1 reference

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Epidermal growth factor-related peptides and their receptors in human malignancies

1 reference

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Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

1 reference

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What Is the Evidence That Tumors Are Angiogenesis Dependent?

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7 April 2017

Vascular endothelial growth factor induced by hypoxia may mediate hypoxia-initiated angiogenesis

1 reference

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7 April 2017

Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy.

1 reference

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29 September 2017

Role of the hypoxia sensing system, acidity and reproductive hormones in the variability of vascular endothelial growth factor induction in human breast carcinoma cell lines

1 reference

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29 September 2017

Constitutive activation of phosphatidylinositol 3-kinase by a naturally occurring mutant epidermal growth factor receptor

1 reference

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29 September 2017

Hypoxia-inducible factor-1 modulates gene expression in solid tumors and influences both angiogenesis and tumor growth.

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Oncogenic H-ras stimulates tumor angiogenesis by two distinct pathways

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Transcription factor AP-1 regulation by mitogen-activated protein kinase signal transduction pathways.

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Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma

1 reference

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Tyrphostin AG 1478 preferentially inhibits human glioma cells expressing truncated rather than wild-type epidermal growth factor receptors

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

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Insulinlike growth factors and binding proteins in colon cancer

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1 reference

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Expression of vascular endothelial growth factor and its receptor, KDR, correlates with vascularity, metastasis, and proliferation of human colon cancer

1 reference

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Specific targeting of a mutant, activated egf receptor found in glioblastoma using a monoclonal antibody

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The implications of angiogenesis for the biology and therapy of cancer metastasis

1 reference

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Anti-synthetic peptide antibody reacting at the fusion junction of deletion-mutant epidermal growth factor receptors in human glioblastoma

1 reference

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29 September 2017

Amplified and rearranged epidermal growth factor receptor genes in human glioblastomas reveal deletions of sequences encoding portions of the N- and/or C-terminal tails

1 reference

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Structural alterations of the epidermal growth factor receptor gene in human gliomas

1 reference

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Normoxic and hypoxic regulation of vascular endothelial growth factor (VEGF) by astrocytoma cells is mediated by Ras.

1 reference

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2 June 2018

Insulin induces transcription of target genes through the hypoxia-inducible factor HIF-1alpha/ARNT

1 reference

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Constitutive activation of c-Jun N-terminal kinase by a mutant epidermal growth factor receptor

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PI3K: downstream AKTion blocks apoptosis

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Altered subcellular location of an activated and tumour-associated epidermal growth factor receptor.

1 reference

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1 reference

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1 reference

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https://pubmed.ncbi.nlm.nih.gov/11355942

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Evaluation of antitumor activity in a human breast tumor/nude mouse model with a special emphasis on treatment dose

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inferred from PubMed ID database lookup

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https://pubmed.ncbi.nlm.nih.gov/11355942

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Protein kinase B is expressed in pancreatic beta cells and activated upon stimulation with insulin-like growth factor I

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inferred from PubMed ID database lookup

Identifiers

10.1054/BJOC.2001.1805

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Consolidated OpenCitations Corpus – April 2017

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OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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PubMed publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

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