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The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness

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23 July 2019

4 August 2019

20 August 2019

18 November 2019

27 November 2019

21 December 2019

1 February 2021

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness (English)

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23 July 2019

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4 August 2019

physiological phenomenon

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20 August 2019

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18 November 2019

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27 November 2019

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21 December 2019

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1 February 2021

Protein C, inactivator of coagulation factors Va and VIIIa

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1 February 2021

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C T Esmon

1

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language of work or name

English

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publication date

2001

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7 references

23 July 2019

4 August 2019

20 August 2019

18 November 2019

27 November 2019

21 December 2019

1 February 2021

5

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2

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page(s)

S7-12

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cites work

Structural basis for the anticoagulant activity of the thrombin-thrombomodulin complex

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PubMed Central

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20 March 2017

TAFI, or plasma procarboxypeptidase B, couples the coagulation and fibrinolytic cascades through the thrombin-thrombomodulin complex

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20 March 2017

Identification, cloning, and regulation of a novel endothelial cell protein C/activated protein C receptor

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20 March 2017

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

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PubMed Central

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20 March 2017

The soluble endothelial protein C receptor binds to activated neutrophils: involvement of proteinase-3 and CD11b/CD18

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PubMed Central

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20 March 2017

Activated protein C inhibits lipopolysaccharide-induced nuclear translocation of nuclear factor kappaB (NF-kappaB) and tumour necrosis factor alpha (TNF-alpha) production in the THP-1 monocytic cell line

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PubMed Central

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3300084

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29 September 2017

Activated protein C suppresses tissue factor expression on U937 cells in the endothelial protein C receptor-dependent manner

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PubMed Central

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29 September 2017

Infectious purpura fulminans: diagnosis and treatment

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29 September 2017

Cell mediated events that control blood coagulation and vascular injury

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PubMed Central

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29 September 2017

Purification and characterization of TAFI, a thrombin-activable fibrinolysis inhibitor

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PubMed Central

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29 September 2017

Activated protein C stimulates the fibrinolytic activity of cultured endothelial cells and decreases antiactivator activity

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PubMed Central

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29 September 2017

C4b-binding protein exacerbates the host response to Escherichia coli

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29 September 2017

Activated protein C reduces ischemia/reperfusion-induced renal injury in rats by inhibiting leukocyte activation

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27 November 2018

Activated protein C reduces the severity of compression-induced spinal cord injury in rats by inhibiting activation of leukocytes

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PubMed Central

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27 November 2018

Use of endothelium cultured on microcarriers as a model for the microcirculation

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PubMed

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https://pubmed.ncbi.nlm.nih.gov/11379986

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Binding of activated protein C to a specific receptor on human mononuclear phagocytes inhibits intracellular calcium signaling and monocyte-dependent proliferative responses

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11379986

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombomodulin overexpression to limit neointima formation

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11379986

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endothelial cell protein C receptor

1 reference

stated in

PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11379986

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The endothelial cell protein C receptor aids in host defense against Escherichia coli sepsis

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PubMed

reference URL

https://pubmed.ncbi.nlm.nih.gov/11379986

retrieved

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

DOI

10.1186/CC1333

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Dimensions Publication ID

1013222163

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PMC publication ID

3300084

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PubMed publication ID

11379986

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ResearchGate publication ID

11958863

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(Q28366000)

The normal role of Activated Protein C in maintaining homeostasis and its relevance to critical illness

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