(Q28366078)

English

Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling

scientific article

In more languages

Statements

scholarly article

0 references

Blood-brain barrier transport and brain distribution of morphine-6-glucuronide in relation to the antinociceptive effect in rats--pharmacokinetic/pharmacodynamic modelling (English)

0 references

0 references

pharmacodynamics

1 reference

based on heuristic

inferred from title

pharmacokinetics

1 reference

based on heuristic

inferred from title

blood–brain barrier

1 reference

based on heuristic

inferred from title

author name string

M R Bouw

1

0 references

R Xie

2

0 references

K Tunblad

3

0 references

M Hammarlund-Udenaes

4

0 references

language of work or name

0 references

publication date

December 2001

0 references

British Journal of Pharmacology

0 references

134

0 references

8

0 references

1796-804

0 references

An improved method for the simultaneous determination of morphine and its principal glucuronide metabolites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 March 2017

Comparison of four basic models of indirect pharmacodynamic responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

29 September 2017

Diffusion of morphine-6-beta-D-glucuronide into the neonatal guinea pig brain during drug-induced respiratory depression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

29 September 2017

Ion diffusion modified by tortuosity and volume fraction in the extracellular microenvironment of the rat cerebellum

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

29 September 2017

Testing computer-controlled infusion pumps by simulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

29 September 2017

Multiple mu opiate receptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

29 September 2017

The role of P-glycoprotein in blood-brain barrier transport of morphine: transcortical microdialysis studies in mdr1a (-/-) and mdr1a (+/+) mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

Concentration-effect relationships of morphine and morphine-6 beta-glucuronide in the rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

Morphine-6-glucuronide: analgesic effects and receptor binding profile in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

Different mu receptor subtypes mediate spinal and supraspinal analgesia in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

Further evidence that morphine-6 beta-glucuronide is a more potent opioid agonist than morphine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

Simultaneous modeling of pharmacokinetics and pharmacodynamics: application to d-tubocurarine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

20 June 2018

A preliminary study on the distribution of morphine and its glucuronides in the subcompartments of blood.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704406

21 January 2018

Modelling of the blood-brain barrier transport of morphine-3-glucuronide studied using microdialysis in the rat: involvement of probenecid-sensitive transport

1 reference

https://api.crossref.org/works/10.1038%2FSJ.BJP.0704406

21 January 2018

Observations on the neuropharmacology of morphine and morphinelike analgesia.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Pharmacokinetic-pharmacodynamic modelling of morphine transport across the blood-brain barrier as a cause of the antinociceptive effect delay in rats--a microdialysis study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Elevated concentrations of morphine 6-beta-D-glucuronide in brain extracellular fluid despite low blood-brain barrier permeability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Methodological aspects of the use of a calibrator in in vivo microdialysis-further development of the retrodialysis method

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Blood-brain barrier permeability to morphine-6-glucuronide is markedly reduced compared with morphine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Octanol−, Chloroform−, and Propylene Glycol Dipelargonat−Water Partitioning of Morphine-6-glucuronide and Other Related Opiates†

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Disposition and analgesic effects of systemic morphine, morphine-6-glucuronide and normorphine in rat.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Morphine-6-glucuronide has high affinity for the opioid receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Morphine-6-glucuronide, a potent mu agonist.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Pharmacological characterization of morphine-6 beta-glucuronide, a very potent morphine metabolite.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1572896

27 November 2018

Delayed antinociceptive effect following morphine-6-glucuronide administration in the rat--pharmacokinetic/pharmacodynamic modelling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Xpose--an S-PLUS based population pharmacokinetic/pharmacodynamic model building aid for NONMEM

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Analgesic Effect of Morphine Glucuronides

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The Effects of Caffeine and Theophylline on Nociceptive Stimulation in the Rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling of tolerance development and rebound effect during different intravenous administrations of morphine to rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantification of effect delay and acute tolerance development to morphine in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Gabapentin anticonvulsant action in rats: disequilibrium with peak drug concentrations in plasma and brain microdialysate

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distribution of morphine 6-glucuronide and morphine across the blood-brain barrier in awake, freely moving rats investigated by in vivo microdialysis sampling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Poor permeability of morphine 3-glucuronide and morphine 6-glucuronide through the blood-brain barrier in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11739257

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0704406

0 references

PMC publication ID

0 references

PubMed publication ID

0 references

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q28366078&oldid=1608363359"