(Q28367213)

English

Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species

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Activation of pro-(matrix metalloproteinase-2) (pro-MMP-2) by thrombin is membrane-type-MMP-dependent in human umbilical vein endothelial cells and generates a distinct 63 kDa active species (English)

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author name string

M A Lafleur

1

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M D Hollenberg

2

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S J Atkinson

3

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V Knäuper

4

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G Murphy

5

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D R Edwards

6

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language of work or name

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publication date

1 July 2001

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Biochemical Journal

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357

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Pt 1

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107-15

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1 reference

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20 March 2017

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Protease-activated receptors 1 and 4 mediate activation of human platelets by thrombin

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Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA

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1 reference

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20 March 2017

Intermolecular autolytic cleavage can contribute to the activation of progelatinase A by cell membranes

1 reference

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1 reference

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How the protease thrombin talks to cells

1 reference

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

29 September 2017

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1 reference

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Matrix metalloproteinases and the development of cancer

1 reference

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29 September 2017

Membrane-type matrix metalloproteinase 1 is a gelatinolytic enzyme and is secreted in a complex with tissue inhibitor of metalloproteinases 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

29 September 2017

The soluble catalytic domain of membrane type 1 matrix metalloproteinase cleaves the propeptide of progelatinase A and initiates autoproteolytic activation. Regulation by TIMP-2 and TIMP-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

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Cloning and expression of a cDNA coding for the anticoagulant hirudin from the bloodsucking leech, Hirudo medicinalis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

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How is blood vessel growth regulated in normal and neoplastic tissue? G.H.A. Clowes memorial Award lecture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

29 September 2017

Thrombin induces endothelial cell growth via both a proteolytic and a non-proteolytic pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

2 June 2018

Furin-independent pathway of membrane type 1-matrix metalloproteinase activation in rabbit dermal fibroblasts

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

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Activation of MMP-2 by human GCT23 giant cell tumour cells induced by osteopontin, bone sialoprotein and GRGDSP peptides is RGD and cell shape change dependent.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1221933

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Pharmacology of hirudin: one hundred years after the first report of the anticoagulant agent in medicinal leeches

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

Thrombin promotes angiogenesis by a mechanism independent of fibrin formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct receptors and signaling pathways in alpha-thrombin- and thrombin receptor peptide-induced vascular contractions

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

Monitoring mRNA expression by polymerase chain reaction: the "primer-dropping" method

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

Thrombin induces the activation of progelatinase A in vascular endothelial cells. Physiologic regulation of angiogenesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma membrane-dependent activation of gelatinase A in human vascular endothelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of human umbilical vein endothelial cell progelatinase A by phorbol myristate acetate: a protein kinase C-dependent mechanism involving a membrane-type matrix metalloproteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin promotes activation of matrix metalloproteinase-2 produced by cultured vascular smooth muscle cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Involvement of PA/plasmin system in the processing of pro-MMP-9 and in the second step of pro-MMP-2 activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

Release of gelatinase A during platelet activation mediates aggregation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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inferred from PubMed ID database lookup

Thrombin promotes endothelial cell alignment in Matrigel in vitro and angiogenesis in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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inferred from PubMed ID database lookup

Vascular endothelial growth factor induces tissue factor and matrix metalloproteinase production in endothelial cells: conversion of prothrombin to thrombin results in progelatinase A activation and cell proliferation

1 reference

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inferred from PubMed ID database lookup

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1 reference

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inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

Evaluation of proteinase-activated receptor-1 (PAR1) agonists and antagonists using a cultured cell receptor desensitization assay: activation of PAR2 by PAR1-targeted ligands

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thrombin rapidly and efficiently activates gelatinase A in human microvascular endothelial cells via a mechanism independent of active MT1 matrix metalloproteinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11415441

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based on heuristic

inferred from PubMed ID database lookup

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