(Q28368896)

English

Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil

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Effects of the non-NMDA antagonists NBQX and the 2,3-benzodiazepine GYKI 52466 on different seizure types in mice: comparison with diazepam and interactions with flumazenil (English)

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author name string

W Löscher

1

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D Hönack

2

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language of work or name

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publication date

December 1994

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British Journal of Pharmacology

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113

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4

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1349-57

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The excitatory amino acid antagonist D-CPP-ene (SDZ EAA-494) in patients with epilepsy

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Therapeutic potential of excitatory amino acid antagonists: channel blockers and 2,3-benzodiazepines

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29 September 2017

Differential pharmacological effects of benzodiazepine receptor inverse agonists

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Anticonvulsant efficacy of clonazepam and the beta-carboline ZK 93423 during chronic treatment in amygdala-kindled rats

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29 September 2017

Which animal models should be used in the search for new antiepileptic drugs? A proposal based on experimental and clinical considerations

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Anticonvulsant drugs: mechanisms of action

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Antispasticity drugs: mechanisms of action

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29 September 2017

The behavioral pharmacology of NMDA receptor antagonists

1 reference

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The NMDA receptor, NMDA antagonists and epilepsy therapy. A status report

1 reference

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Relief of experimental spasticity and anxiolytic/anticonvulsant actions of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate antagonist 2,3-dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline

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29 September 2017

The depressant effect of GYKI 52466 on spinal reflex transmission in rats is mediated via non-NMDA and benzodiazepine receptors.

1 reference

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2 June 2018

GYKI 52466, a 2,3-benzodiazepine, is a highly selective, noncompetitive antagonist of AMPA/kainate receptor responses

1 reference

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Is the muscle relaxant effect of diazepam in spastic mutant rats mediated through GABA-independent benzodiazepine receptors?

1 reference

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Benzodiazepine antagonist Ro 15-1788: Neurological and behavioral effects

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Evaluation of CPP, a selective NMDA antagonist, in various rodent models of epilepsy. Comparison with other NMDA antagonists, and with diazepam and phenobarbital.

1 reference

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1 reference

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New quinoxalinediones show potent antagonism of quisqualate responses in cultured mouse cortical neurons

1 reference

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2 June 2018

Electrophysiological studies with a 2,3-benzodiazepine muscle relaxant: GYKI 52466.

1 reference

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2 June 2018

The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. II. Maximal electroshock seizure models

1 reference

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Is GABA release modulated by presynaptic excitatory amino acid receptors?

1 reference

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Differential effects of the excitatory amino acid antagonists, 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) and 3-((+-)-2-carboxypiperazin-4-yl)-propyl-1-phosphonic acid (CPP), on spinal reflex activity in mice.

1 reference

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Pharmacological properties of the N-methyl-D-aspartate receptor system coupled to the evoked release of gamma-[3H] aminobutyric acid from striatal neurons in primary culture

1 reference

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1 reference

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Effect of the benzodiazepine receptor antagonist Ro 15-1788 on the anticonvulsant and anticonflict actions of MK-801.

1 reference

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21 January 2018

The effect of the non-NMDA receptor antagonist GYKI 52466 and NBQX and the competitive NMDA receptor antagonist D-CPPene on the development of amygdala kindling and on amygdala-kindled seizures

1 reference

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Reversal of the anticonvulsant effects of diazepam on amygdaloid-kindled seizures by a specific benzodiazepine antagonist: RO 15-1788.

1 reference

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1 reference

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2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(F)quinoxaline enhances the protective activity of common antiepileptic drugs against maximal electroshock-induced seizures in mice.

1 reference

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A benzodiazepine recognition site associated with the non-NMDA glutamate receptor

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NMDA receptor antagonists decrease GABA outflow from the septum and increase acetylcholine outflow from the hippocampus: a microdialysis study.

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Selective antagonists of benzodiazepines

1 reference

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Chemical protection against ionizing radiation. I. Sampling methods for screening compounds in radiation protection studies with mice

1 reference

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Excitatory amino acid-evoked release of gamma-[3H]aminobutyric acid from striatal neurons in primary culture

1 reference

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Anticonvulsant and behavioral effects of two novel competitive N-methyl-D-aspartic acid receptor antagonists, CGP 37849 and CGP 39551, in the kindling model of epilepsy. Comparison with MK-801 and carbamazepine

1 reference

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The role of technical, biological and pharmacological factors in the laboratory evaluation of anticonvulsant drugs. III. Pentylenetetrazole seizure models

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

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inferred from PubMed ID database lookup

The anticonvulsant effect of the non-NMDA antagonists, NBQX and GYKI 52466, in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

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based on heuristic

inferred from PubMed ID database lookup

Probenecid pretreatment enhances anticonvulsant action of NBQX in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anticonvulsant activity of AMPA/kainate antagonists: comparison of GYKI 52466 and NBOX in maximal electroshock and chemoconvulsant seizure models

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

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based on heuristic

inferred from PubMed ID database lookup

Low doses of NMDA receptor antagonists synergistically increase the anticonvulsant effect of the AMPA receptor antagonist NBQX in the kindling model of epilepsy

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

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based on heuristic

inferred from PubMed ID database lookup

Many agents that antagonize the NMDA receptor-channel complex in vivo also cause disturbances of motor coordination

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relationship between GABA concentrations in cerebrospinal fluid and seizure excitability

1 reference

https://pubmed.ncbi.nlm.nih.gov/7889291

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1111/J.1476-5381.1994.TB17146.X

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