(Q28369425)

English

Stability-activity relationships of a family of G-tetrad forming oligonucleotides as potent HIV inhibitors. A basis for anti-HIV drug design

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scholarly article

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Stability-activity relationships of a family of G-tetrad forming oligonucleotides as potent HIV inhibitors. A basis for anti-HIV drug design (English)

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author name string

N Jing

1

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E De Clercq

2

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R F Rando

3

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L Pallansch

4

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C Lackman-Smith

5

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S Lee

6

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M E Hogan

7

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language of work or name

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publication date

4 February 2000

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Journal of Biological Chemistry

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275

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5

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3421-30

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Toward improved anti-HIV chemotherapy: therapeutic strategies for intervention with HIV infections

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Administration of 3'-azido-3'-deoxythymidine, an inhibitor of HTLV-III/LAV replication, to patients with AIDS or AIDS-related complex

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Inhibition of the in vitro infectivity and cytopathic effect of human T-lymphotrophic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV) by 2',3'-dideoxynucleosides

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Phase I studies of 2',3'-dideoxycytidine in severe human immunodeficiency virus infection as a single agent and alternating with zidovudine (AZT).

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2',3'-didehydro-3'-deoxythymidine (d4T) in patients with AIDS or AIDS-related complex: a phase I trial

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A pilot study of low-dose zidovudine in human immunodeficiency virus infection

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Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy

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Recovery of replication-competent HIV despite prolonged suppression of plasma viremia

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Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy

1 reference

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Suppression of human immunodeficiency virus type 1 activity in vitro by oligonucleotides which form intramolecular tetrads

1 reference

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Inhibition of the human immunodeficiency virus type 1 integrase by guanosine quartet structures

1 reference

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Ion selective folding of loop domains in a potent anti-HIV oligonucleotide

1 reference

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Potassium-induced loop conformational transition of a potent anti-HIV oligonucleotide

1 reference

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Structure-activity of tetrad-forming oligonucleotides as a potent anti-HIV therapeutic drug

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Thermodynamic and spectroscopic study of bulge loops in oligoribonucleotides.

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Potent and selective inhibition of human immunodeficiency virus (HIV)-1 and HIV-2 replication by a class of bicyclams interacting with a viral uncoating event

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A DNA aptamer which binds to and inhibits thrombin exhibits a new structural motif for DNA.

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Three-dimensional solution structure of the thrombin-binding DNA aptamer d(GGTTGGTGTGGTTGG)

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The retroviral enzymes

1 reference

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Domains of the integrase protein of human immunodeficiency virus type 1 responsible for polynucleotidyl transfer and zinc binding

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Crystal structure of the catalytic domain of HIV-1 integrase: similarity to other polynucleotidyl transferases

1 reference

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Solution structure of the N-terminal zinc binding domain of HIV-1 integrase

1 reference

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Solution structure of the DNA binding domain of HIV-1 integrase

1 reference

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The DNA-binding domain of HIV-1 integrase has an SH3-like fold

1 reference

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Identifiers

10.1074/JBC.275.5.3421

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release_wpda4rmn5zfyzfijoo45g6pmp4

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