(Q28370578)

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Inhibition of L-homocysteic acid and buthionine sulphoximine-mediated neurotoxicity in rat embryonic neuronal cultures with alpha-lipoic acid enantiomers

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scholarly article

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Inhibition of L-homocysteic acid and buthionine sulphoximine-mediated neurotoxicity in rat embryonic neuronal cultures with alpha-lipoic acid enantiomers (English)

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1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

toxic encephalopathy

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based on heuristic

inferred from title

author name string

B Lockhart

1

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C Jones

2

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C Cuisinier

3

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N Villain

4

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D Peyroulan

5

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P Lestage

6

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language of work or name

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publication date

14 February 2000

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855

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292-7

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2

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Protection against oxidative stress-induced neuronal cell death--a novel role for RU486.

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Reduction of lipoic acid by lipoamide dehydrogenase

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The pharmacology of the antioxidant lipoic acid

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Uptake of glutamate and cysteine in C-6 glioma cells and in cultured astrocytes.

1 reference

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Lipoic acid increases de novo synthesis of cellular glutathione by improving cystine utilization

1 reference

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Cytosolic and mitochondrial systems for NADH- and NADPH-dependent reduction of alpha-lipoic acid

1 reference

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Promotion of cystine uptake and its utilization for glutathione biosynthesis induced by cysteamine and N-acetylcysteine

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Dihydrolipoic acid--a universal antioxidant both in the membrane and in the aqueous phase. Reduction of peroxyl, ascorbyl and chromanoxyl radicals

1 reference

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A mechanism for glutamate toxicity in the C6 glioma cells involving inhibition of cystine uptake leading to glutathione depletion

1 reference

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Stereospecific effects of R-lipoic acid on buthionine sulfoximine-induced cataract formation in newborn rats

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Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

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Prolonged pretreatment with alpha-lipoic acid protects cultured neurons against hypoxic, glutamate-, or iron-induced injury.

1 reference

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Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

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Vulnerability of oligodendroglia to glutamate: pharmacology, mechanisms, and prevention.

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Neuroprotection by the metabolic antioxidant alpha-lipoic acid

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alpha-Lipoic acid protects against reperfusion injury following cerebral ischemia in rats

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Macromolecular synthesis inhibitors prevent oxidative stress-induced apoptosis in embryonic cortical neurons by shunting cysteine from protein synthesis to glutathione.

1 reference

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Thioctic Acid and Dihydrolipoic Acid are Novel Antioxidants Which Interact With Reactive Oxygen Species

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Neuroprotective effects of alpha-lipoic acid and its enantiomers demonstrated in rodent models of focal cerebral ischemia.

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Reactive oxygen species involved in the glutamate toxicity of C6 glioma cells via xc antiporter system.

1 reference

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Identifiers

10.1016/S0006-8993(99)02372-0

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release_53mowc6rqza5vhehmveu3oibma

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