(Q28372970)

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Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates

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title

Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates (English)

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author name string

N R Wurtz

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1

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P B Dervan

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2

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language of work or name

English

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publication date

March 2000

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published in

Chemistry and Biology

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volume

7

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issue

3

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page(s)

153-61

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cites work

Recognition of DNA by designed ligands at subnanomolar concentrations

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Cooperative Hairpin Dimers for Recognition of DNA by Pyrrole-Imidazole Polyamides

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Sequence-specific DNA recognition by polyamides

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Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin

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On the pairing rules for recognition in the minor groove of DNA by pyrrole-imidazole polyamides

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Structural basis for G.C recognition in the DNA minor groove

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A structural basis for recognition of A.T and T.A base pairs in the minor groove of B-DNA

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A Pyrrole-Imidazole Polyamide Motif for Recognition of Eleven Base Pair Sequences in the Minor Groove of DNA

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Sequence specificity of alkylation for a series of nitrogen mustard-containing analogues of distamycin of increasing binding site size: evidence for increased cytotoxicity with enhanced sequence specificity.

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Structure-activity relationship of a series of C-terminus modified aminoalkyl, diaminoalkyl- and anilino-containing analogues of the benzoic acid mustard distamycin derivative tallimustine: synthesis, DNA binding and cytotoxicity studies

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Identifiers

DOI

10.1016/S1074-5521(00)00085-5

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PubMed ID

10712931

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(Q28372970)

Sequence specific alkylation of DNA by hairpin pyrrole-imidazole polyamide conjugates

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