(Q28373081)

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Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

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Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs (English)

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M J Prieto-Alamo

1

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F Laval

series ordinal

2

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language of work or name

English

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publication date

March 1999

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published in

Carcinogenesis

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volume

20

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issue

3

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page(s)

415-9

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cites work

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Repair of intrinsic DNA lesions

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Isolation of cDNA clones encoding a human apurini/apyrimidinic endonuclease that corects DNA repair and mutagenisis defects inE.coli xth(exonuclease III) mutants

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21 January 2018

Cloning and expression of APE, the cDNA encoding the major human apurinic endonuclease: definition of a family of DNA repair enzymes

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21 January 2018

Role of cysteine residues in regulation of p53 function

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21 January 2018

Asparagine 212 is essential for abasic site recognition by the human DNA repair endonuclease HAP1

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21 January 2018

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

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21 January 2018

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

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21 January 2018

Reduction of Radiation Cytotoxicity by Human Apurinic Endonuclease in a Radiation-Sensitive Escherichia coli Mutant

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21 January 2018

Expression of the E. coli fpg gene in mammalian cells reduces the mutagenicity of gamma-rays

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Increased resistance of the Chinese hamster mutant irsl cells to monofunctional alkylating agents by transfection of the E. coli or mammalian N3-methyladenine-DNA-glycosylase genes

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Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression.

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21 January 2018

Removal of 3'-phosphoglycolate from DNA strand-break damage in an oligonucleotide substrate by recombinant human apurinic/apyrimidinic endonuclease 1

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Trans-complementation by human apurinic endonuclease (Ape) of hypersensitivity to DNA damage and spontaneous mutator phenotype in apn1-yeast

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Stable expression in rat glioma cells of sense and antisense nucleic acids to a human multifunctional DNA repair enzyme, APEX nuclease

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The redox/DNA repair protein, Ref-1, is essential for early embryonic development in mice.

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21 January 2018

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

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21 January 2018

Effect of site-specifically located mitomycin C-DNA monoadducts on in vitro DNA synthesis by DNA polymerases.

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21 January 2018

Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct

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21 January 2018

Differential toxicity of mitomycin C and porfiromycin to aerobic and hypoxic Chinese hamster ovary cells overexpressing human NADPH:cytochrome c (P-450) reductase

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21 January 2018

Identifiers

DOI

10.1093/CARCIN/20.3.415

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PubMed publication ID

10190555

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ResearchGate publication ID

13106718

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(Q28373081)

Overexpression of the human HAP1 protein sensitizes cells to the lethal effect of bioreductive drugs

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