(Q28373219)

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Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export

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Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export (English)

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N A Davarinos

1

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R S Pollenz

2

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publication date

1 October 1999

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Journal of Biological Chemistry

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274

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40

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28708-15

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cDNA cloning and structure of mouse putative Ah receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Cloning of the Ah-receptor cDNA reveals a distinctive ligand-activated transcription factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

The aryl hydrocarbon receptor complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Mechanistic aspects of dioxin action

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Prolonged depletion of AH receptor without alteration of receptor mRNA levels after treatment of cells in culture with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Characterization of polyclonal antibodies to the aromatic hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Ah receptor and ARNT protein and mRNA concentrations in rat prostate: effects of stage of development and 2,3,7, 8-tetrachlorodibenzo-p-dioxin treatment.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Down-regulation of nuclear aryl hydrocarbon receptor DNA-binding and transactivation functions: requirement for a labile or inducible factor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Mechanism of dioxin action: receptor-enhancer interactions in intact cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Species-specific recombinant cell lines as bioassay systems for the detection of 2,3,7,8-tetrachlorodibenzo-p-dioxin-like chemicals

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Proteasomes: structure and biology

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Involvement of proteasomes in regulating Jak-STAT pathways upon interleukin-2 stimulation.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Proteasome inhibition leads to a heat-shock response, induction of endoplasmic reticulum chaperones, and thermotolerance

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Regulation of hypoxia-inducible factor 1alpha is mediated by an O2-dependent degradation domain via the ubiquitin-proteasome pathway

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Structure and functions of the 20S and 26S proteasomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Nuclear export signals and the fast track to the cytoplasm.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Nuclear localization and export signals of the human aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Leptomycin B inhibition of signal-mediated nuclear export by direct binding to CRM1

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Molecular cloning and cell cycle-dependent expression of mammalian CRM1, a protein involved in nuclear export of proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Mutation of a protease-sensitive region in firefly luciferase alters light emission properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

A very sensitive coupled luminescent assay for cytotoxicity and complement-mediated lysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Comparison of the nuclear and cytosolic forms of the Ah receptor from Hepa 1c1c7 cells: charge heterogeneity and ATP binding properties

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Functional characterization of DNA-binding domains of the subunits of the heterodimeric aryl hydrocarbon receptor complex imputing novel and canonical basic helix-loop-helix protein-DNA interactions.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Dioxin-dependent activation of murine Cyp1a-1 gene transcription requires protein kinase C-dependent phosphorylation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Inhibitors of serine/threonine-specific protein phosphatases stimulate transcription by the Ah receptor/Arnt dimer by affecting a step subsequent to XRE binding

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

An alphabeta T cell receptor structure at 2.5 A and its orientation in the TCR-MHC complex

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Role of kinases and the phosphatase calcineurin in the nuclear shuttling of transcription factor NF-AT4.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Control of gene expression by proteolysis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

The ubiquitin-proteasome pathway is required for processing the NF-kappa B1 precursor protein and the activation of NF-kappa B

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Activation of Hypoxia-inducible Factor-1; Definition of Regulatory Domains within the α Subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Hypoxia-inducible factor 1alpha (HIF-1alpha) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions. Its stabilization by hypoxia depends on redox-induced changes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Hypoxia-inducible factor 1 and the molecular physiology of oxygen homeostasis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

The murine Sim-2 gene product inhibits transcription by active repression and functional interference

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Two new members of the murine Sim gene family are transcriptional repressors and show different expression patterns during mouse embryogenesis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Possible function of Ah receptor nuclear translocator (Arnt) homodimer in transcriptional regulation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

DNA Binding Specificities and Pairing Rules of the Ah Receptor, ARNT, and SIM Proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Protein kinase C modulates aryl hydrocarbon receptor nuclear translocator protein-mediated transactivation potential in a dimer context

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Abnormal angiogenesis and responses to glucose and oxygen deprivation in mice lacking the protein ARNT.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

ARNT-deficient mice and placental differentiation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

Amelioration of TCDD-induced teratogenesis in aryl hydrocarbon receptor (AhR)-null mice

1 reference

https://api.crossref.org/works/10.1074%2FJBC.274.40.28708

21 January 2018

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