(Q28376645)

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Activation of cGMP-dependent protein kinase Ialpha is required for N-methyl-D-aspartate- or nitric oxide-produced spinal thermal hyperalgesia

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Activation of cGMP-dependent protein kinase Ialpha is required for N-methyl-D-aspartate- or nitric oxide-produced spinal thermal hyperalgesia (English)

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author name string

Y X Tao

1

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R A Johns

2

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language of work or name

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publication date

31 March 2000

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European Journal of Pharmacology

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392

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3

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141-5

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Nitric oxide, a novel neuronal messenger

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(Rp)-8-pCPT-cGMPS, a novel cGMP-dependent protein kinase inhibitor.

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Antagonism at the glycine site on the NMDA receptor reduces spinal nociception in the rat

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Intrathecal injection of cell-permeable analogs of cyclic 3',5'-guanosine monophosphate produces hyperalgesia in mice

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Carrageenan-induced inflammation alters the content of i-cGMP and i-cAMP in the dorsal horn of the spinal cord

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Sodium nitroprusside evokes the release of immunoreactive calcitonin gene-related peptide and substance P from dorsal horn slices via nitric oxide-dependent and nitric oxide-independent mechanisms.

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Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain

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Intrathecal administration of a new nitric oxide donor, NOC-18, produces acute thermal hyperalgesia in the rat.

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Glutamate receptor agonists stimulate nitric oxide synthase in primary cultures of cerebellar granule cells

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Induction of spinal cord neuronal nitric oxide synthase (NOS) after formalin injection in the rat hind paw

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Intracellular cyclic GMP receptor proteins.

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Spinal nitric oxide synthesis inhibition blocks NMDA-induced thermal hyperalgesia and produces antinociception in the formalin test in rats

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Production of endogenous nitric oxide and activation of soluble guanylate cyclase are required for N-methyl-D-aspartate-produced facilitation of the nociceptive tail-flick reflex

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Nitric oxide (NO) and nociceptive processing in the spinal cord

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Nitric oxide mediates the thermal hyperalgesia produced in a model of neuropathic pain in the rat

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L-NG-nitro arginine methyl ester exhibits antinociceptive activity in the mouse

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Nitric oxide (NO) release by glutamate and NMDA in the dorsal horn of the spinal cord: an in vivo electrochemical approach in the rat.

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Attenuation of NMDA-induced spinal hypersensitivity by adrenal medullary transplants

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The effects of G-protein and protein kinase inhibitors on the behavioral responses of rats to intradermal injection of capsaicin

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Expression and action of cyclic GMP-dependent protein kinase Ialpha in inflammatory hyperalgesia in rat spinal cord

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Identifiers

10.1016/S0014-2999(00)00129-1

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