(Q28387028)

1

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Yiran Zhang

2

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Liang Ma

3

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Yiming Ni

4

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Haige Zhao

Role of Nrf2 in oxidative stress and toxicity

5

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language of work or name

English

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publication date

12 April 2016

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published in

Oncotarget

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volume

7

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issue

15

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page(s)

19272-83

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cites work

1 reference

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BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

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Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

20 March 2017

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Enhancing Nrf2 pathway by disruption of Keap1 in myeloid leukocytes protects against sepsis

29 September 2017

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KEAP1 gene mutations and NRF2 activation are common in pulmonary papillary adenocarcinoma

29 September 2017

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Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance

29 September 2017

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Deletion of Keap1 in the lung attenuates acute cigarette smoke-induced oxidative stress and inflammation

29 September 2017

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PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

29 September 2017

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Disruption of Nrf2, a key inducer of antioxidant defenses, attenuates ApoE-mediated atherosclerosis in mice

29 September 2017

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Burn-induced gut barrier injury is attenuated by phosphodiesterase inhibition: effects on tight junction structural proteins

29 September 2017

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Altered Nrf2/Keap1-Bach1 equilibrium in pulmonary emphysema

29 September 2017

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Heme oxygenase-1 protects against neutrophil-mediated intestinal damage by down-regulation of neutrophil p47phox and p67phox activity and O2- production in a two-hit model of alcohol intoxication and burn injury

29 September 2017

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Preclinical evaluation of targeting the Nrf2 pathway by triterpenoids (CDDO-Im and CDDO-Me) for protection from LPS-induced inflammatory response and reactive oxygen species in human peripheral blood mononuclear cells and neutrophils

29 September 2017

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Role of HMGB1 in apoptosis-mediated sepsis lethality

29 September 2017

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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

29 September 2017

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Burns, bacterial translocation, gut barrier function, and failure

29 September 2017

1 reference

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Role of the gut in the development of injury- and shock induced SIRS and MODS: the gut-lymph hypothesis, a review

29 September 2017

1 reference

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Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice

29 September 2017

1 reference

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Regulation of cytokine production in human alveolar macrophages and airway epithelial cells in response to ambient air pollution particles: further mechanistic studies

29 September 2017

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Role of the gastrointestinal tract in burn sepsis

29 September 2017

1 reference

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Nrf2 signaling in coordinated activation of antioxidant gene expression

29 September 2017

1 reference

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Free radicals and lipid peroxidation mediated injury in burn trauma: the role of antioxidant therapy

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

Intestinal damage mediated by Kupffer cells in rats with endotoxemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound

29 September 2017

1 reference

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Post-injury multiple organ failure: the role of the gut.

29 September 2017

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Role of the gut in multiple organ failure: bacterial translocation and permeability changes

29 September 2017

1 reference

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Burns, inflammation, and intestinal injury: protective effects of an anti-inflammatory resuscitation strategy

29 September 2017

1 reference

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Nrf2-dependent protection from LPS induced inflammatory response and mortality by CDDO-Imidazolide

2 June 2018

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Gut-derived mesenteric lymph but not portal blood increases endothelial cell permeability and promotes lung injury after hemorrhagic shock.

2 June 2018

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Nrf2 is a critical modulator of the innate immune response in a model of uveitis

2 June 2018

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Increased intestinal inflammatory response and gut barrier dysfunction in Nrf2-deficient mice after traumatic brain injury

27 November 2018

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Pentoxifylline attenuates lung injury and modulates transcription factor activity in hemorrhagic shock

27 November 2018

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Induction of heme oxygenase-1 improves impaired intestinal transit after burn injury.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

LPS-stimulated PMN activation and proinflammatory mediator synthesis is downregulated by phosphodiesterase inhibition: role of pentoxifylline

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

Cholinergic agonists inhibit HMGB1 release and improve survival in experimental sepsis

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

Plasma oxidative parameters and mortality in patients with severe burn injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

Relationships between burn size, immunosuppression, and macrophage hyperactivity in a murine model of thermal injury

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4991382

A positive approach to burn care

27 November 2018

1 reference

12 December 2020

Intestinal cytokine response after gut ischemia: role of gut barrier failure

1 reference

12 December 2020

Cardiac mitochondrial damage and loss of ROS defense after burn injury: the beneficial effects of antioxidant therapy

1 reference

12 December 2020

The effect of antioxidant therapy on cell-mediated immunity following burn injury in an animal model

1 reference

12 December 2020

Role of thermal injury-induced hypoproteinemia on fluid flux and protein permeability in burned and nonburned tissue

1 reference

12 December 2020

Bacterial translocation after burn injury: the contribution of ischemia and permeability changes

1 reference

12 December 2020