(Q28397887)

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Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Mediates Neuroprotection in Traumatic Brain Injury at Least in Part by Inactivating Microglia

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Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Mediates Neuroprotection in Traumatic Brain Injury at Least in Part by Inactivating Microglia (English)

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traumatic brain injury

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author name string

Gang Wu

1

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Zongying Liu

2

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language of work or name

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publication date

23 June 2016

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Medical Science Monitor

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22

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2161-6

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Vacuolar leukoencephalopathy with widespread astrogliosis in mice lacking transcription factor Nrf2

1 reference

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19 March 2017

Temporal changes in cell marker expression and cellular infiltration in a controlled cortical impact model in adult male C57BL/6 mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

19 March 2017

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

7 April 2017

Monocyte and macrophage heterogeneity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

7 April 2017

The many faces of macrophage activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

7 April 2017

Contributions of the immune system to the pathophysiology of traumatic brain injury - evidence by intravital microscopy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Microglia activation as a biomarker for traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Transcription factor Nrf2 suppresses LPS-induced hyperactivation of BV-2 microglial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Role of microglia in neurotrauma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Microglial phenotype is regulated by activity of the transcription factor, NFAT (nuclear factor of activated T cells).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Chronic upregulation of activated microglia immunoreactive for galectin-3/Mac-2 and nerve growth factor following diffuse axonal injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

IL-6: from its discovery to clinical applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

A protective role of nuclear factor-erythroid 2-related factor-2 (Nrf2) in inflammatory disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Disruption of Nrf2 enhances upregulation of nuclear factor-kappaB activity, proinflammatory cytokines, and intercellular adhesion molecule-1 in the brain after traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

The transcription factor Nrf2 is a therapeutic target against brain inflammation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Microglia biology in health and disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Role of Nrf2 in protection against intracerebral hemorrhage injury in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Microglia repetitively isolated from in vitro mixed glial cultures retain their initial phenotype

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Role of reactive oxygen species in modulation of Nrf2 following ischemic reperfusion injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

The Nrf2-ARE Signalling pathway: promising drug target to combat oxidative stress in neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

An important role of Nrf2-ARE pathway in the cellular defense mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

NF-E2-related factor-2 mediates neuroprotection against mitochondrial complex I inhibitors and increased concentrations of intracellular calcium in primary cortical neurons

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

Microglia: a sensor to threats in the nervous system?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

29 September 2017

In situ detection of inflammatory mediators in post mortem human brain tissue after traumatic injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

2 June 2018

A small-molecule-inducible Nrf2-mediated antioxidant response provides effective prophylaxis against cerebral ischemia in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

2 June 2018

Inflammation and immune system activation after traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Microglia activation along the corticospinal tract following traumatic brain injury in the rat: a neuroanatomical study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Inflammation after trauma: microglial activation and traumatic brain injury.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Transcription factor Nrf2 plays a pivotal role in protection against traumatic brain injury-induced acute intestinal mucosal injury in mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Neuronal sensitivity to kainic acid is dependent on the Nrf2-mediated actions of the antioxidant response element.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Sulforaphane enhances aquaporin-4 expression and decreases cerebral edema following traumatic brain injury

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4922828

27 November 2018

Cytokine appearance in human endotoxemia and primate bacteremia

1 reference

https://pubmed.ncbi.nlm.nih.gov/27336674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia: Intrinsic immuneffector cell of the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/27336674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pathophysiology of traumatic brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/27336674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rapid and widespread microglial activation induced by traumatic brain injury in rat brain slices

1 reference

https://pubmed.ncbi.nlm.nih.gov/27336674

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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