(Q28477525)

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Point mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reduction

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Point mutations in Helicobacter pylori's fur regulatory gene that alter resistance to metronidazole, a prodrug activated by chemical reduction (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Helicobacter pylori

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1 reference

based on heuristic

inferred from title

Peter T Chivers

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

author name string

Sung Sook Choi

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

Douglas E Berg

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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25 March 2011

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

6

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

e18236

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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Creative Commons Attribution 4.0 International

25 March 2011

1 reference

April 2022 Public Data File from Crossref

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0 references

The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

The primary transcriptome of the major human pathogen Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Structural characterization of the active form of PerR: insights into the metal-induced activation of PerR and Fur proteins for DNA binding

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Helicobacter pylori usurps cell polarity to turn the cell surface into a replicative niche

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Crystal structure of the Vibrio cholerae ferric uptake regulator (Fur) reveals insights into metal co-ordination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Mycobacterium tuberculosis DosS is a redox sensor and DosT is a hypoxia sensor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

UCSF Chimera--a visualization system for exploratory research and analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

The spatial orientation of Helicobacter pylori in the gastric mucus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Architecture of a protein central to iron homeostasis: crystal structure and spectroscopic analysis of the ferric uptake regulator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

The protein-protein interaction map of Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

Structure of the metal-ion-activated diphtheria toxin repressor/tox operator complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

The complete genome sequence of the gastric pathogen Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

19 March 2017

The N-terminal arm of the Helicobacter pylori Ni2+-dependent transcription factor NikR is required for specific DNA binding.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

7 April 2017

Role of innate immunity in Helicobacter pylori-induced gastric malignancy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Geobacter uraniireducens NikR displays a DNA binding mode distinct from other members of the NikR family

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Regulatory circuits in Helicobacter pylori : network motifs and regulators involved in metal-dependent responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Helicobacter pylori in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

This is not your mother's repressor: the complex role of fur in pathogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Development of inducible systems to engineer conditional mutants of essential genes of Helicobacter pylori

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Balancing the double-edged sword: metal ion homeostasis and the ulcer bug.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Functional specialization within the Fur family of metalloregulators

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

The Helicobacter pylori chemotaxis receptor TlpB (HP0103) is required for pH taxis and for colonization of the gastric mucosa

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Motility of urease-deficient derivatives of Helicobacter pylori.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Roles of FrxA and RdxA nitroreductases of Helicobacter pylori in susceptibility and resistance to metronidazole

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Systematic identification of selective essential genes in Helicobacter pylori by genome prioritization and allelic replacement mutagenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Mouse-colonizing Helicobacter pylori SS1 is unusually susceptible to metronidazole due to two complementary reductase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Metronidazole activation is mutagenic and causes DNA fragmentation in Helicobacter pylori and in Escherichia coli containing a cloned H. pylori RdxA(+) (Nitroreductase) gene

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Arm-domain interactions in AraC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

The role of fur in the acid tolerance response of Salmonella typhimurium is physiologically and genetically separable from its role in iron acquisition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

29 September 2017

Mutagenesis of conserved amino acids of Helicobacter pylori fur reveals residues important for function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064673

2 June 2018

Structural changes of Escherichia coli ferric uptake regulator during metal-dependent dimerization and activation explored by NMR and X-ray crystallography.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Mutation discovery in bacterial genomes: metronidazole resistance in Helicobacter pylori.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Mapping arm-DNA-binding domain interactions in AraC.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Metronidazole resistance in Helicobacter pylori is due to null mutations in a gene (rdxA) that encodes an oxygen-insensitive NADPH nitroreductase

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Characterization of the DNA-binding site in the ferric uptake regulator protein from Escherichia coli by UV crosslinking and mass spectrometry

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Individual metal ligands play distinct functional roles in the zinc sensor Staphylococcus aureus CzrA.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Transcriptional profiling of Helicobacter pylori Fur- and iron-regulated gene expression

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Helicobacter pylori tissue tropism: mouse-colonizing strains can target different gastric niches

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

The PerR transcription factor senses H2O2 by metal-catalysed histidine oxidation

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0018236

21 January 2018

Two amino acids mutation of ferric uptake regulator determines Helicobacter pylori resistance to metronidazole

1 reference

https://pubmed.ncbi.nlm.nih.gov/21464913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The N-terminal arms of lambda repressor wrap around the operator DNA

1 reference

https://pubmed.ncbi.nlm.nih.gov/21464913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repressor structure and the mechanism of positive control

1 reference

https://pubmed.ncbi.nlm.nih.gov/21464913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Crystal structure of the apo-PerR-Zn protein from Bacillus subtilis

1 reference

https://pubmed.ncbi.nlm.nih.gov/21464913

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0018236

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

2011PLoSO...618236C

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21464913%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

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