(Q28478912)

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2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease

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2-Deoxy-D-glucose treatment induces ketogenesis, sustains mitochondrial function, and reduces pathology in female mouse model of Alzheimer's disease (English)

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Alzheimer's disease

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based on heuristic

inferred from title

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inferred from title

author name string

Jia Yao

1

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Shuhua Chen

2

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Zisu Mao

3

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Enrique Cadenas

4

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Roberta Diaz Brinton

5

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language of work or name

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publication date

2011

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6

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e21788

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7

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Creative Commons Attribution 4.0 International

1 July 2011

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April 2022 Public Data File from Crossref

copyright status

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Regional aerobic glycolysis in the human brain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Spatial correlation between brain aerobic glycolysis and amyloid-β (Aβ ) deposition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Chronic ingestion of 2-deoxy-D-glucose induces cardiac vacuolization and increases mortality in rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Hypometabolism as a therapeutic target in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

The neuroprotective properties of calorie restriction, the ketogenic diet, and ketone bodies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Neuroprotective and disease-modifying effects of the ketogenic diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Effects of caloric restriction on mitochondrial function and gene transcripts in rat muscle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

Fatty acid oxidation and ketogenesis by astrocytes in primary culture

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

19 March 2017

A catabolic block does not sufficiently explain how 2-deoxy-D-glucose inhibits cell growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

7 April 2017

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

7 April 2017

Triple-transgenic model of Alzheimer's disease with plaques and tangles: intracellular Abeta and synaptic dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

7 April 2017

Intracellular amyloid-beta in Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

7 April 2017

Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

New views of Arc, a master regulator of synaptic plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Characterizing Alzheimer's disease using a hypometabolic convergence index

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Targeting tumor metabolism with 2-deoxyglucose in patients with castrate-resistant prostate cancer and advanced malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Alzheimer's disease: diverse aspects of mitochondrial malfunctioning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Decline in mitochondrial bioenergetics and shift to ketogenic profile in brain during reproductive senescence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Amyloid-beta and mitochondria in aging and Alzheimer's disease: implications for synaptic damage and cognitive decline

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Clinical studies for improving radiotherapy with 2-deoxy-D-glucose: present status and future prospects.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Mitochondria: a therapeutic target in neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

The neurodegenerative mitochondriopathies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

FDG-PET changes in brain glucose metabolism from normal cognition to pathologically verified Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

The healthy cell bias of estrogen action: mitochondrial bioenergetics and neurological implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Estrogen regulation of glucose metabolism and mitochondrial function: therapeutic implications for prevention of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Turning down tau phosphorylation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Progesterone and estrogen regulate oxidative metabolism in brain mitochondria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Mechanisms of impaired mitochondrial energy metabolism in acute and chronic neurodegenerative disorders

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Intermittent fasting and caloric restriction ameliorate age-related behavioral deficits in the triple-transgenic mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Hippocampal hypometabolism predicts cognitive decline from normal aging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Moderate consumption of Cabernet Sauvignon attenuates Abeta neuropathology in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Neuron-glia metabolic coupling and plasticity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Mitochondria take center stage in aging and neurodegeneration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Mitochondrial dysfunction and Alzheimer's disease: role of amyloid-beta peptide alcohol dehydrogenase (ABAD).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Cerebral ketone body metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Ketone body synthesis in the brain: possible neuroprotective effects

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Dietary restriction normalizes glucose metabolism and BDNF levels, slows disease progression, and increases survival in huntingtin mutant mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Inherent abnormalities in energy metabolism in Alzheimer disease. Interaction with cerebrovascular compromise

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

29 September 2017

Drug/diet synergy for managing malignant astrocytoma in mice: 2-deoxy-D-glucose and the restricted ketogenic diet

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

2 June 2018

Dietary restriction increases the number of newly generated neural cells, and induces BDNF expression, in the dentate gyrus of rats.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

2 June 2018

Inhibition of established rat fibrosarcoma growth by the glucose antagonist 2-deoxy-D-glucose.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

2 June 2018

Abnormalities of Glucose Metabolism in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

2 June 2018

ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Mitochondrial free radical production and cell signaling

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Spatial exploration-induced Arc mRNA and protein expression: evidence for selective, network-specific reactivation.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Caloric restriction attenuates Abeta-deposition in Alzheimer transgenic models

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Dietary restriction stimulates BDNF production in the brain and thereby protects neurons against excitotoxic injury

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Preservation of heat stress induced myocardial hsp 72 in aged animals following caloric restriction.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Improving cancer radiotherapy with 2-deoxy-D-glucose: phase I/II clinical trials on human cerebral gliomas.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

Dietary supplementation with 2-deoxy-D-glucose improves cardiovascular and neuroendocrine stress adaptation in rats

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0021788

21 January 2018

ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

27 November 2018

Caloric restriction attenuates beta-amyloid neuropathology in a mouse model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

27 November 2018

Dietary restriction and 2-deoxyglucose administration reduce focal ischemic brain damage and improve behavioral outcome: evidence for a preconditioning mechanism.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

27 November 2018

Dietary restriction and 2-deoxyglucose administration improve behavioral outcome and reduce degeneration of dopaminergic neurons in models of Parkinson's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

27 November 2018

Reduction of cerebellar glucose metabolism in advanced Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3128612

27 November 2018

Identifiers

10.1371/JOURNAL.PONE.0021788

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https://api.fatcat.wiki/v0/release/yhjb3rru2vf5zochgjnna5m5ka

30 July 2022

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2011PLoSO...621788Y

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release_yhjb3rru2vf5zochgjnna5m5ka

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https://api.fatcat.wiki/v0/release/yhjb3rru2vf5zochgjnna5m5ka

30 July 2022

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

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https://api.fatcat.wiki/v0/release/yhjb3rru2vf5zochgjnna5m5ka

30 July 2022

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https://api.fatcat.wiki/v0/release/yhjb3rru2vf5zochgjnna5m5ka

30 July 2022

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