(Q28479342)

English

Identification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugs

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scholarly article

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Identification of inhibitors against Mycobacterium tuberculosis thiamin phosphate synthase, an important target for the development of anti-TB drugs (English)

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Mycobacterium tuberculosis

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author name string

Garima Khare

1

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Ritika Kar

2

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Anil K Tyagi

3

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language of work or name

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publication date

2011

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6

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7

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e22441

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copyright license

Creative Commons Attribution 4.0 International

26 July 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

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Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?

1 reference

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19 March 2017

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19 March 2017

Clustal W and Clustal X version 2.0

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19 March 2017

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

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19 March 2017

UCSF Chimera--a visualization system for exploratory research and analysis

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19 March 2017

Thiamine triphosphate and thiamine triphosphatase activities: from bacteria to mammals

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19 March 2017

SWISS-MODEL: An automated protein homology-modeling server

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19 March 2017

Genes required for mycobacterial growth defined by high density mutagenesis

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19 March 2017

Comparative genomics of thiamin biosynthesis in procaryotes. New genes and regulatory mechanisms

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19 March 2017

Structural characterization of the enzyme-substrate, enzyme-intermediate, and enzyme-product complexes of thiamin phosphate synthase

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Crystal structure of thiamin phosphate synthase from Bacillus subtilis at 1.25 A resolution

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19 March 2017

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19 March 2017

Recognition of errors in three-dimensional structures of proteins

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Death resulting from fatty acid starvation in yeast.

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1 reference

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1 reference

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19 March 2017

Assessment of protein models with three-dimensional profiles

1 reference

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19 March 2017

Genetic requirements for mycobacterial survival during infection

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7 April 2017

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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7 April 2017

ProSA-web: interactive web service for the recognition of errors in three-dimensional structures of proteins

1 reference

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7 April 2017

Verification of protein structures: patterns of nonbonded atomic interactions

1 reference

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7 April 2017

NAD+ auxotrophy is bacteriocidal for the tubercle bacilli

1 reference

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Thiamin diphosphate in biological chemistry: new aspects of thiamin metabolism, especially triphosphate derivatives acting other than as cofactors

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29 September 2017

Structure, mechanism and catalytic duality of thiamine-dependent enzymes

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29 September 2017

Virtual ligand screening: strategies, perspectives and limitations

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29 September 2017

A low-molecular-weight compound discovered through virtual database screening inhibits Stat3 function in breast cancer cells

1 reference

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29 September 2017

A genetic screen for the identification of thiamin metabolic genes

1 reference

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29 September 2017

The biosynthesis of thiamine. 2. Fractionation of enzyme system and identification of thiazole monophosphate and thiamine monophosphate as intermediates.

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Unbalanced growth of yeast due to inositol deficiency

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29 September 2017

Can correct protein models be identified?

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29 September 2017

Further development and validation of empirical scoring functions for structure-based binding affinity prediction

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Thiamin biosynthesis in prokaryotes

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29 September 2017

Characterization of the Bacillus subtilis thiC operon involved in thiamine biosynthesis

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29 September 2017

14 Thiamine phosphate pyrophosphorylase

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29 September 2017

Purification and properties of thiaminephosphate pyrophosphorylase of Escherichia coli

1 reference

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2 June 2018

Inositol-requiring mutants of Saccharomyces cerevisiae

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2 June 2018

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PROCHECK: a program to check the stereochemical quality of protein structures

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1 reference

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1 reference

https://pubmed.ncbi.nlm.nih.gov/21818324

12 December 2020

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Identifiers

10.1371/JOURNAL.PONE.0022441

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2011PLoSO...622441K

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PMC publication ID

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PubMed publication ID

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