(Q28482364)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

title

Proteins from Avastin® (bevacizumab) show tyrosine nitrations for which the consequences are completely unclear (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Gert Lubec

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

author name string

Jia Wan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Edina Csaszar

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

Kongzhao Li

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

language of work or name

English

0 references

publication date

16 April 2012

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

issue

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

page(s)

e34511

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

29 January 2020

copyright license

start time

16 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Crystal structure of the antioxidant enzyme glutathione reductase inactivated by peroxynitrite

1 reference

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Peroxynitrite: biochemistry, pathophysiology and development of therapeutics

19 March 2017

1 reference

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Bevacizumab improves quality of life in patients with recurrent glioblastoma.

7 April 2017

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29 September 2017

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Increased risk of serious hemorrhage with bevacizumab in cancer patients: a meta-analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

The addition of new drugs to standard therapy in the first-line treatment of ovarian cancer

29 September 2017

1 reference

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Bevacizumab: current updates in treatment

29 September 2017

1 reference

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A safety and survival analysis of neoadjuvant bevacizumab with standard chemoradiation in a phase I/II study compared with standard chemoradiation in locally advanced rectal cancer

29 September 2017

1 reference

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Bevacizumab increases risk for severe proteinuria in cancer patients

29 September 2017

1 reference

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Bevacizumab toxicities and their management in ovarian cancer

29 September 2017

1 reference

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Collateral damage: toxic effects of targeted antiangiogenic therapies in ovarian cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Increased risk of high-grade hypertension with bevacizumab in cancer patients: a meta-analysis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Anti-vascular endothelial growth factor therapies and cardiovascular toxicity: what are the important clinical markers to target?

29 September 2017

1 reference

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Cutaneous side effects of inhibition of VEGF signal transduction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Protein tyrosine nitration: selectivity, physicochemical and biological consequences, denitration, and proteomics methods for the identification of tyrosine-nitrated proteins.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Evaluation of the sterility, stability, and efficacy of bevacizumab stored in multiple-dose vials for 6 months

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Protein tyrosine nitration--an update

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Fibrinogen beta-chain tyrosine nitration is a prothrombotic risk factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Factors that contribute to the misidentification of tyrosine nitration by shotgun proteomics.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Nitration in neurodegeneration: deciphering the "Hows" "nYs".

29 September 2017

1 reference

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Identification of immunoglobulins that recognize 3-nitrotyrosine in patients with acute lung injury after major trauma

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

The highly conserved Glu149 and Tyr190 residues contribute to peroxynitrite-mediated nitrotyrosine formation and the catalytic activity of cytochrome P450 2B1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Oxidative stress and nitration in neurodegeneration: cause, effect, or association?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Requirements for heme and thiols for the nonenzymatic modification of nitrotyrosine

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Nitration and inactivation of manganese superoxide dismutase in chronic rejection of human renal allografts

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3327692

Overall survival with cisplatin-gemcitabine and bevacizumab or placebo as first-line therapy for nonsquamous non-small-cell lung cancer: results from a randomised phase III trial (AVAiL)

29 September 2017

1 reference

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Silk cocoon of Bombyx mori: proteins and posttranslational modifications--heavy phosphorylation and evidence for lysine-mediated cross links

2 June 2018

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Effectiveness of bevacizumab- and pemetrexed-cisplatin treatment for patients with advanced non-squamous non-small cell lung cancer

2 June 2018

1 reference

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Gel-based mass spectrometric analysis of a strongly hydrophobic GABAA-receptor subunit containing four transmembrane domains

21 January 2018

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Detection of sequence-specific tyrosine nitration of manganese SOD and SERCA in cardiovascular disease and aging.

21 January 2018

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Pro-thrombotic state induced by post-translational modification of fibrinogen by reactive nitrogen species.

21 January 2018

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Mutation of tyrosine 190 to alanine eliminates the inactivation of cytochrome P450 2B1 by peroxynitrite

21 January 2018

1 reference

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Tyrosine modifications and inactivation of active site manganese superoxide dismutase mutant (Y34F) by peroxynitrite

21 January 2018

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12 December 2020

Final overall survival results and effect of prolonged (≥ 1 year) first-line bevacizumab-containing therapy for metastatic breast cancer in the ATHENA trial

1 reference

12 December 2020

Subcellular localization of tyrosine-nitrated proteins is dictated by reactive oxygen species generating enzymes and by proximity to nitric oxide synthase

1 reference

12 December 2020

1 reference

12 December 2020

Conversion of 3-nitrotyrosine to 3-aminotyrosine in peptides and proteins

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0034511

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

22523550

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22523550%20AND%20SRC:MED&resulttype=core&format=json