(Q28482436)

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Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer

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scholarly article

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Cysteamine suppresses invasion, metastasis and prolongs survival by inhibiting matrix metalloproteinases in a mouse model of human pancreatic cancer (English)

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pancreatic cancer

1 reference

based on heuristic

inferred from title

author name string

Toshio Fujisawa

1

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Benjamin Rubin

2

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Akiko Suzuki

3

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Prabhudas S Patel

4

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William A Gahl

5

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Bharat H Joshi

6

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Raj K Puri

7

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language of work or name

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publication date

2012

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7

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4

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e34437

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copyright license

Creative Commons CC0 License

20 April 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted, dedicated to the public domain by copyright holder

0 references

Randomized phase III trial of marimastat versus placebo in patients with metastatic breast cancer who have responding or stable disease after first-line chemotherapy: Eastern Cooperative Oncology Group trial E2196

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New strategy of efficient inhibition of cancer cells by carborane carboxylic acid-CdTe nanocomposites.

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29 September 2017

Gold nanoparticle probes: design and in vitro applications in cancer cell culture

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29 September 2017

Interleukin-13 receptor α2 DNA prime boost vaccine induces tumor immunity in murine tumor models

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29 September 2017

Solanum nigrum Linn. Water Extract Inhibits Metastasis in Mouse Melanoma Cells in Vitro and in Vivo

1 reference

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29 September 2017

Pharmacokinetics of enteric-coated cysteamine bitartrate in healthy adults: a pilot study.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

29 September 2017

Targeting IL-13Rα2 in human pancreatic ductal adenocarcinoma with combination therapy of IL-13-PE and gemcitabine

1 reference

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29 September 2017

A novel role of interleukin-13 receptor alpha2 in pancreatic cancer invasion and metastasis

1 reference

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29 September 2017

Pharmacological treatment of nephropathic cystinosis with cysteamine

1 reference

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29 September 2017

A novel matrix metalloproteinase inhibitor, FYK-1388 suppresses tumor growth, metastasis and angiogenesis by human fibrosarcoma cell line.

1 reference

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29 September 2017

The many faces of metalloproteases: cell growth, invasion, angiogenesis and metastasis

1 reference

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29 September 2017

Ongoing trials with matrix metalloproteinase inhibitors

1 reference

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29 September 2017

Marimastat (BB2516): current status of development

1 reference

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29 September 2017

Inhibition of the proliferation of human neural neoplastic cell lines by cysteamine

1 reference

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29 September 2017

Tumor rejection in experimental animals treated with radioprotective thiols

1 reference

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29 September 2017

Matrix metalloproteinases as stromal effectors of human carcinoma progression: therapeutic implications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

2 June 2018

Distribution of extracellular matrix proteins in pancreatic ductal adenocarcinoma and its influence on tumor cell proliferation in vitro.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

2 June 2018

A Comparison of the Effectiveness of Cysteamine and Phosphocysteamine in Elevating Plasma Cysteamine Concentration and Decreasing Leukocyte Free Cystine in Nephropathic Cystinosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

2 June 2018

Inhibitory effect of prolonged administration of cysteamine on experimental carcinogenesis in rat stomach induced by N-methyl-N'-nitro-N-nitrosoguanidine.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

2 June 2018

Possible oncostatic action of cysteamine on the pituitary glands of oestrogen-primed hyperprolactinaemic rats

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3332081

2 June 2018

The killing effect of 4-S-cysteaminylphenol, a newly synthesised melanin precursor, on B16 melanoma cell lines

1 reference

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2 June 2018

Long-term treatment of cystinosis in children with twice-daily cysteamine

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034437

21 January 2018

Matrix metalloproteinase inhibitor RO 28-2653 decreases liver metastasis by reduction of MMP-2 and MMP-9 concentration in BOP-induced ductal pancreatic cancer in Syrian Hamsters: inhibition of matrix metalloproteinases in pancreatic cancer.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034437

21 January 2018

Interleukin 13 mediates signal transduction through interleukin 13 receptor alpha2 in pancreatic ductal adenocarcinoma: role of IL-13 Pseudomonas exotoxin in pancreatic cancer therapy

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034437

21 January 2018

The evaluation and treatment of gastrointestinal disease in children with cystinosis receiving cysteamine

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0034437

21 January 2018

Understanding intestinal cysteamine bitartrate absorption

1 reference

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21 January 2018

Increased expression of matrix metalloproteinases (MMP)-2, MMP-9, and the urokinase-type plasminogen activator is associated with progression from benign to advanced ovarian cancer

1 reference

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27 November 2018

The effects of ranitidine and cysteamine on intestinal metaplasia induced by X-irradiation in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved renal function in children with cystinosis treated with cysteamine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effects of cysteamine on the upper gastrointestinal tract of children with cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stromal degradation by the malignant epithelium in pancreatic cancer and the therapeutic potential of proteolytic inhibition

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and intracellular localization of matrix metalloproteinases in intraductal papillary mucinous neoplasms of the pancreas

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

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based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics of cysteamine in a cystinosis patient treated with hemodialysis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Autophagy-mediated chemosensitization by cysteamine in cancer cells

1 reference

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inferred from PubMed ID database lookup

Inhibitory effects of WR-2721 and cysteamine on tumor initiation in mammary glands of pregnant rats by radiation

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Authentic matrix vesicles contain active metalloproteases (MMP). a role for matrix vesicle-associated MMP-13 in activation of transforming growth factor-beta

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Plasma cysteamine concentrations in children treated for cystinosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

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based on heuristic

inferred from PubMed ID database lookup

Combination therapy including a gelatinase inhibitor and cytotoxic agent reduces local invasion and metastasis of murine Lewis lung carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

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based on heuristic

inferred from PubMed ID database lookup

Control of lymphatic and hematogenous metastasis of a rat mammary carcinoma by the matrix metalloproteinase inhibitor batimastat (BB-94)

1 reference

https://pubmed.ncbi.nlm.nih.gov/22532830

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0034437

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2012PLoSO...734437F

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PMC publication ID

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PubMed publication ID

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