(Q28483745)

1

0 references

Shupeng Liu

2

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Jinliang Peng

3

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Xiaohui Wei

4

0 references

Ye Sun

5

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Yangsheng Qiu

6

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Guangwei Gao

7

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Peng Wang

8

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Yuhong Xu

Creative Commons Attribution 4.0 International

9

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language of work or name

English

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publication date

2012

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published in

PLOS One

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volume

7

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issue

5

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page(s)

e37098

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copyright license

start time

16 May 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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Phage display: selecting straws instead of a needle from a haystack.

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The identification of cellular targets of 17β estradiol using a lytic (T7) cDNA phage display approach

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Identification of sex hormone binding globulin-interacting proteins in the brain using phage display screening

29 September 2017

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Identifying the proteins to which small-molecule probes and drugs bind in cells

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Natural products and drug discovery. Can thousands of years of ancient medical knowledge lead us to new and powerful drug combinations in the fight against cancer and dementia?

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Huperzine A provides neuroprotection against several cell death inducers using in vitro model systems of motor neuron cell death

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29 September 2017

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Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695.

29 September 2017

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Diazonamide toxins reveal an unexpected function for ornithine delta-amino transferase in mitotic cell division

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Mitoenergetic failure in Alzheimer disease

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Mitochondria are a direct site of A beta accumulation in Alzheimer's disease neurons: implications for free radical generation and oxidative damage in disease progression

29 September 2017

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Oxidation-reduction respiratory chains and ATP synthase complex are localized in detergent-resistant lipid rafts

29 September 2017

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Huperzine A protects SHSY5Y neuroblastoma cells against oxidative stress damage via nerve growth factor production

29 September 2017

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Neuroprotective effects of huperzine A. A natural cholinesterase inhibitor for the treatment of Alzheimer's disease

29 September 2017

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Using genome-wide transcriptional profiling to elucidate small-molecule mechanism

29 September 2017

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A genome-wide overexpression screen in yeast for small-molecule target identification

29 September 2017

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Biomarkers for apoptosis in Alzheimer's disease

29 September 2017

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Huperzine A enhances the level of secretory amyloid precursor protein and protein kinase C-alpha in intracerebroventricular beta-amyloid-(1-40) infused rats and human embryonic kidney 293 Swedish mutant cells

29 September 2017

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Macromolecule-ligand binding studied by the Hummel and Dreyer method: current state of the methodology

29 September 2017

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Capillary electrophoresis frontal analysis: principles and applications for the study of drug-plasma protein binding

29 September 2017

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Apoptosis in Alzheimer's disease--an update

29 September 2017

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Identification of amino acid residues involved in the binding of Huperzine A to cholinesterases

29 September 2017

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Huperzine A exhibits anti-inflammatory and neuroprotective effects in a rat model of transient focal cerebral ischemia

29 September 2017

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Huperzine A attenuates cognitive dysfunction and neuronal degeneration caused by beta-amyloid protein-(1-40) in rat.

21 January 2018

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Huperzine A attenuates mitochondrial dysfunction after middle cerebral artery occlusion in rats

21 January 2018

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Huperzine A attenuates cognitive deficits and brain injury in neonatal rats after hypoxia-ischemia.

21 January 2018

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Enantiodifferential approach for the detection of the target membrane protein of the jasmonate glycoside that controls the leaf movement of Albizzia saman

21 January 2018

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Target identification using drug affinity responsive target stability (DARTS)

21 January 2018

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Synthesis and characterization of iron oxide/polymer composite nanoparticles with pendent functional groups.

21 January 2018

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Ampicillin/penicillin-binding protein interactions as a model drug-target system to optimize affinity pull-down and mass spectrometric strategies for target and pathway identification

21 January 2018

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Rational design and synthesis of highly potent anti-acetylcholinesterase activity huperzine A derivatives

21 January 2018

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Prediction of the binding sites of huperzine A in acetylcholinesterase by docking studies.

21 January 2018

1 reference

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Huperzine A attenuates mitochondrial dysfunction in beta-amyloid-treated PC12 cells by reducing oxygen free radicals accumulation and improving mitochondrial energy metabolism

21 January 2018

1 reference

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Huperzine A protects isolated rat brain mitochondria against beta-amyloid peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

A selective defect of cytochrome c oxidase is present in brain of Alzheimer disease patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

The role of cytochrome c oxidase deficient hippocampal neurones in Alzheimer's disease

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

Copper-dependent inhibition of human cytochrome c oxidase by a dimeric conformer of amyloid-beta1-42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

BIACORE analysis of histidine-tagged proteins using a chelating NTA sensor chip.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

Direct detection of glucose by surface plasmon resonance with bacterial glucose/galactose-binding protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0037098

Increased lipid peroxidation precedes amyloid plaque formation in an animal model of Alzheimer amyloidosis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3353884

Huperzine A, a novel promising acetylcholinesterase inhibitor.

27 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3353884

Polyproline-rod approach to isolating protein targets of bioactive small molecules: isolation of a new target of indomethacin

27 November 2018

1 reference

12 December 2020

Isolation and identification of diadenosine 5',5'''-P1,P4-tetraphosphate binding proteins using magnetic bio-panning

1 reference

12 December 2020

Protective effects of huperzine A on β-amyloid25–35 induced oxidative injury in rat pheochromocytoma cells

1 reference

12 December 2020

Huperzine A attenuates hydrogen peroxide-induced apoptosis by regulating expression of apoptosis-related genes in rat PC12 cells

1 reference

12 December 2020

Comparison of five methods for the study of drug-protein binding in affinity capillary electrophoresis

1 reference

12 December 2020

Drug target validation and identification of secondary drug target effects using DNA microarrays

1 reference

12 December 2020