(Q28505199)

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Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

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PubMed publication ID

24 January 2017

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site (English)

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

Glutamate receptor, ionotropic, NMDA1 (zeta 1)

1 reference

GOA release 2020-03-11

author name string

J N Kew

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

A Koester

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

J L Moreau

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

F Jenck

4

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

A M Ouagazzal

5

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

V Mutel

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

J G Richards

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

G Trube

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

G Fischer

9

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

A Montkowski

10

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

W Hundt

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

R K Reinscheid

12

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

M Pauly-Evers

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

J A Kemp

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

H Bluethmann

15

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

language of work or name

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publication date

1 June 2000

1 reference

PubMed publication ID

24 January 2017

Journal of Neuroscience

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

20

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

11

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

4037-4049

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

Cloning and expression of the epsilon 4 subunit of the NMDA receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation kinetics reveal the number of glutamate and glycine binding sites on the N-methyl-d-aspartate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of N-methyl-D-aspartate receptors in the induction of synaptic potentiation by burst stimulation patterned after the hippocampal theta-rhythm

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Zinc potentiates agonist-induced currents at certain splice variants of the NMDA receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological properties of recombinant human N-methyl-D-aspartate receptors comprising NR1a/NR2A and NR1a/NR2B subunit assemblies expressed in permanently transfected mouse fibroblast cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Agonist response kinetics of N-methyl-D-aspartate receptors in neurons cultured from rat cerebral cortex and cerebellum: evidence for receptor heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine site of the NMDA receptor--five years on.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Disruption of prepulse inhibition and increases in locomotor activity by competitive N-methyl-D-aspartate receptor antagonists in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetic analysis of antagonist action at N-methyl-D-aspartic acid receptors. Two binding sites each for glutamate and glycine

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A synaptic model of memory: long-term potentiation in the hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comprehensive observational assessment: Ia. A systematic, quantitative procedure for assessing the behavioral and physiologic state of the mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

ACEA 1021, a glycine site antagonist with minor psychotomimetic and amnestic effects in rats.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Place navigation impaired in rats with hippocampal lesions

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine/NMDA receptor antagonist, L-701,324 reverses isolation-induced deficits in prepulse inhibition in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two glycine transporter variants with distinct localization in the CNS and peripheral tissues are encoded by a common gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Competitive NMDA and strychnine-insensitive glycine-site antagonists disrupt prepulse inhibition.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multiple limbic regions mediate the disruption of prepulse inhibition produced in rats by the noncompetitive NMDA antagonist dizocilpine.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Anxiolytic effect of glycine antagonists microinjected into the dorsal periaqueductal grey.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Whisker-related neuronal patterns fail to develop in the trigeminal brainstem nuclei of NMDAR1 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new generation of Ca2+ indicators with greatly improved fluorescence properties

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacological characterization of MDL 105,519, an NMDA receptor glycine site antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: identification of novel determinants of co-agonist potentiation in the extracellular M3-M4 loop region.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular determinants of agonist discrimination by NMDA receptor subunits: analysis of the glutamate binding site on the NR2B subunit

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental and regional expression in the rat brain and functional properties of four NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modulation of N-methyl-D-aspartate receptor function by glycine transport

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine uptake governs glycine site occupancy at NMDA receptors of excitatory synapses

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ro 25-6981, a highly potent and selective blocker of N-methyl-D-aspartate receptors containing the NR2B subunit. Characterization in vitro.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stoichiometry of recombinant N-methyl-D-aspartate receptor channels inferred from single-channel current patterns

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pentameric subunit stoichiometry of a neuronal glutamate receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structures and properties of seven isoforms of the NMDA receptor generated by alternative splicing

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cloning and expression of a glycine transporter reveal colocalization with NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The essential role of hippocampal CA1 NMDA receptor-dependent synaptic plasticity in spatial memory

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mutational analysis of the glycine-binding site of the NMDA receptor: structural similarity with bacterial amino acid-binding proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine transporters are differentially expressed among CNS cells.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental changes in NMDA receptor glycine affinity and ifenprodil sensitivity reveal three distinct populations of NMDA receptors in individual rat cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Heteromeric NMDA receptors: molecular and functional distinction of subtypes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Biochemical evidence for the co-association of three N-methyl-D-aspartate (NMDA) R2 subunits in recombinant NMDA receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A characterization of anxiolytic-like actions induced by the novel NMDA/glycine site antagonist, L-701,324.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impairment of suckling response, trigeminal neuronal pattern formation, and hippocampal LTD in NMDA receptor epsilon 2 subunit mutant mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Concentrations of amino acids in extracellular fluid after opening of the blood-brain barrier by intracarotid infusion of protamine sulfate

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for a tetrameric structure of recombinant NMDA receptors.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Glycine potentiates the NMDA response in cultured mouse brain neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Developmental changes in distribution of NMDA receptor channel subunit mRNAs.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Control of NMDA receptor activation by a glycine transporter co-expressed in Xenopus oocytes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of the strychnine-insensitive glycine binding site in the nucleus accumbens and anterodorsal striatum in sensorimotor gating: a behavioral and microdialysis study.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro binding properties in rat brain of [3H]Ro 25-6981, a potent and selective antagonist of NMDA receptors containing NR2B subunits.

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement for glycine in activation of NMDA-receptors expressed in Xenopus oocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Molecular diversity of the NMDA receptor channel

1 reference

https://pubmed.ncbi.nlm.nih.gov/10818139

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.20-11-04037.2000

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

PubMed publication ID

2 references

PubMed publication ID

24 January 2017

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6772652&resulttype=core&format=json

12 May 2020

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