(Q28506096)

24 January 2017

title

Pharmacological prion protein silencing accelerates central nervous system autoimmune disease via T cell receptor signalling (English)

1 reference

24 January 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

1 reference

21

0 references

author name string

Wei Hu

1

1 reference

24 January 2017

Stefan Nessler

2

1 reference

24 January 2017

Bernhard Hemmer

3

1 reference

24 January 2017

Todd N. Eagar

4

1 reference

24 January 2017

Lawrence P. Kane

5

1 reference

24 January 2017

S. Rutger Leliveld

6

1 reference

24 January 2017

Andreas Müller-Schiffmann

7

1 reference

24 January 2017

Anne R. Gocke

8

1 reference

24 January 2017

Amy Lovett-Racke

9

1 reference

24 January 2017

Li-Hong Ben

10

1 reference

24 January 2017

Rehana Z. Hussain

11

1 reference

24 January 2017

Andreas Breil

12

1 reference

24 January 2017

Jeffrey L. Elliott

13

1 reference

24 January 2017

Krishna Puttaparthi

14

1 reference

24 January 2017

Petra D. Cravens

15

1 reference

24 January 2017

Mahendra P. Singh

16

1 reference

24 January 2017

Benjamin Petsch

17

1 reference

24 January 2017

Lothar Stitz

18

1 reference

24 January 2017

Michael K. Racke

19

1 reference

24 January 2017

Carsten Korth

20

1 reference

24 January 2017

language of work or name

English

0 references

publication date

1 February 2010

1 reference

24 January 2017

1 reference

24 January 2017

volume

133

1 reference

24 January 2017

issue

Pt 2

1 reference

24 January 2017

page(s)

375–388

1 reference

describes a project that uses

24 January 2017

ImageQuant

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2822628/fullTextXML

inferred from PubMed Central ID database lookup

cites work

ZAP-70: a 70 kd protein-tyrosine kinase that associates with the TCR zeta chain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Complementarity determining regions of an anti-prion protein scFv fragment orchestrate conformation specificity and antiprion activity

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Immunomodulatory synergy by combination of atorvastatin and glatiramer acetate in treatment of CNS autoimmunity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Prion protein induced signaling cascades in monocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Silencing T-bet defines a critical role in the differentiation of autoreactive T lymphocytes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Prion protein is a component of the multimolecular signaling complex involved in T cell activation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

The role of the MHC class II transactivator in class II expression and antigen presentation by astrocytes and in susceptibility to central nervous system autoimmune disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

The normal cellular prion protein is strongly expressed by myeloid dendritic cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Prion protein (PrP) with amino-proximal deletions restoring susceptibility of PrP knockout mice to scrapie.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Both a monoclonal antibody and antisera specific for determinants unique to individual cloned helper T cell lines can substitute for antigen and antigen-presenting cells in the activation of T cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Absence of the cellular prion protein exacerbates and prolongs neuroinflammation in experimental autoimmune encephalomyelitis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

PrPc glycoform heterogeneity as a function of brain region: implications for selective targeting of neurons by prion strains

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Mechanisms of T cell activation by the calcium ionophore ionomycin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Cellular isoform of the scrapie agent protein participates in lymphocyte activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

A role of cellular prion protein in programming T-cell cytokine responses in disease

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Perturbation of T-cell development by insertional mutation of a PrP transgene.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Aggregate formation in the spinal cord of mutant SOD1 transgenic mice is reversible and mediated by proteasomes

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

The HMG-CoA reductase inhibitor, atorvastatin, promotes a Th2 bias and reverses paralysis in central nervous system autoimmune disease

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

The expression and potential function of cellular prion protein in human lymphocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

129/Ola mice carrying a null mutation in PrP that abolishes mRNA production are developmentally normal

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Transgenic mice that express a myelin basic protein-specific T cell receptor develop spontaneous autoimmunity

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Leu 23 induction as an early marker of functional CD3/T cell antigen receptor triggering. Requirement for receptor cross-linking, prolonged elevation of intracellular [Ca++] and stimulation of protein kinase C.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2822628

Differential expression of cellular prion protein on human blood and tonsil lymphocytes

27 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145049

12 December 2020

inferred from PubMed ID database lookup

High incidence of spontaneous autoimmune encephalomyelitis in immunodeficient anti-myelin basic protein T cell receptor transgenic mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145049

12 December 2020

inferred from PubMed ID database lookup

The sevenfold way of PKC regulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20145049

12 December 2020

inferred from PubMed ID database lookup

Identifiers

0 references

0 references

1 reference