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V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption
scientific journal article
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scholarly article
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
title
V-ATPase subunit ATP6AP1 (Ac45) regulates osteoclast differentiation, extracellular acidification, lysosomal trafficking, and protease exocytosis in osteoclast-mediated bone resorption
(English)
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
main subject
exocytosis
1 reference
based on heuristic
inferred from title
RAB7, member RAS oncogene family
1 reference
stated in
GOA release 2020-03-11
ATPase, H+ transporting, lysosomal V1 subunit B2
1 reference
stated in
GOA release 2020-03-11
ATPase, H+ transporting, lysosomal accessory protein 1
1 reference
stated in
GOA release 2020-03-11
author name string
De-Qin Yang
series ordinal
1
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
Shengmei Feng
series ordinal
2
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
Wei Chen
series ordinal
3
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
Haibo Zhao
series ordinal
4
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
Christie Paulson
series ordinal
5
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
Yi-Ping Li
series ordinal
6
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
publication date
1 August 2012
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
published in
Journal of Bone and Mineral Research
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
volume
27
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
issue
8
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
page(s)
1695–1707
1 reference
stated in
PubMed
PubMed ID
22467241
retrieved
24 January 2017
cites work
Adhesion structures and their cytoskeleton-membrane interactions at podosomes of osteoclasts in culture
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PubMed Central
reference URL
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19 March 2017
DC-STAMP is essential for cell-cell fusion in osteoclasts and foreign body giant cells
1 reference
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PubMed Central
reference URL
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19 March 2017
Possible role of direct Rac1-Rab7 interaction in ruffled border formation of osteoclasts
1 reference
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PubMed Central
reference URL
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19 March 2017
Intracellular membrane trafficking pathways in bone-resorbing osteoclasts revealed by cloning and subcellular localization studies of small GTP-binding rab proteins
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PubMed Central
reference URL
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19 March 2017
Downregulation of small GTPase Rab7 impairs osteoclast polarization and bone resorption
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
Bone resorption by osteoclasts
1 reference
stated in
PubMed Central
reference URL
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19 March 2017
Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency
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PubMed Central
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19 March 2017
Heterogeneity of vacuolar H(+)-ATPase: differential expression of two human subunit B isoforms
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PubMed Central
reference URL
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19 March 2017
Genetic regulation of osteoclast development and function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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7 April 2017
Induction and activation of the transcription factor NFATc1 (NFAT2) integrate RANKL signaling in terminal differentiation of osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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7 April 2017
Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Cytosolic pH is a second messenger for glucose and regulates the PKA pathway through V-ATPase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
Signaling networks that control the lineage commitment and differentiation of bone cells
1 reference
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PubMed Central
reference URL
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retrieved
29 September 2017
Atp6v0d2 is an essential component of the osteoclast-specific proton pump that mediates extracellular acidification in bone resorption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
Coordinated protein sorting, targeting and distribution in polarized cells
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PubMed Central
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29 September 2017
Vesicular trafficking in osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
The V-type H+-ATPase in vesicular trafficking: targeting, regulation and function
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Cytoplasmic terminus of vacuolar type proton pump accessory subunit Ac45 is required for proper interaction with V(0) domain subunits and efficient osteoclastic bone resorption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Vacuolar-type proton ATPase as regulator of membrane dynamics in multicellular organisms
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
NFATc1 induces osteoclast fusion via up-regulation of Atp6v0d2 and the dendritic cell-specific transmembrane protein (DC-STAMP).
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Structure and function of V-ATPases in osteoclasts: potential therapeutic targets for the treatment of osteolysis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
MAPK signal specificity: the right place at the right time
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PubMed Central
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29 September 2017
Intracellular membrane trafficking in bone resorbing osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
Survival analysis of genome-wide gene expression profiles of prostate cancers identifies new prognostic targets of disease relapse.
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PubMed Central
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29 September 2017
From lysosomes to the plasma membrane: localization of vacuolar-type H+ -ATPase with the a3 isoform during osteoclast differentiation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
Targeted disruption of the mouse gene encoding the V-ATPase accessory subunit Ac45.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
Osteoclastic acidification pathways during bone resorption
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
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29 September 2017
The cell biology of osteoclast function.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Intracellular trafficking of the vacuolar H+-ATPase accessory subunit Ac45.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Cell-mediated extracellular acidification and bone resorption: evidence for a low pH in resorbing lacunae and localization of a 100-kD lysosomal membrane protein at the osteoclast ruffled border
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Osteoclastic bone resorption by a polarized vacuolar proton pump
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
29 September 2017
Atp6v1c1 is an essential component of the osteoclast proton pump and in F-actin ring formation in osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
2 June 2018
The V-ATPase subunit C binds to polymeric F-actin as well as to monomeric G-actin and induces cross-linking of actin filaments
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
2 June 2018
Evidence for the presence of a proton pump of the vacuolar H(+)-ATPase type in the ruffled borders of osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
2 June 2018
Atp6i-deficient mice exhibit severe osteopetrosis due to loss of osteoclast-mediated extracellular acidification.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FJBMR.1623
retrieved
21 January 2018
The fate of newly synthesized V-ATPase accessory subunit Ac45 in the secretory pathway
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1002%2FJBMR.1623
retrieved
21 January 2018
Endocytic pathway from the basal plasma membrane to the ruffled border membrane in bone-resorbing osteoclasts
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3951719
retrieved
27 November 2018
Osteoclast ruffled border has distinct subdomains for secretion and degraded matrix uptake
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22467241
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1002/JBMR.1623
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1238806
OpenCitations bibliographic resource ID
1238806
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1238806
PMCID
3951719
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1238806
PubMed ID
22467241
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
1238806
ResearchGate publication ID
223979955
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