(Q28509846)

21 June 2017

Thyroid hormone signaling in vivo requires a balance between coactivators and corepressors (English)

1 reference

Nuclear receptor coactivator 1

21 June 2017

1 reference

Nuclear receptor corepressor 1

GOA release 2020-03-11

1 reference

Nuclear receptor coactivator 2

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author name string

Preeti Ramadoss

2

1 reference

21 June 2017

Inna Astapova

4

1 reference

21 June 2017

Kristen R Vella

1

1 reference

21 June 2017

Ricardo H Costa-E-Sousa

3

1 reference

21 June 2017

Felix D Ye

5

1 reference

21 June 2017

Kaila A Holtz

6

1 reference

21 June 2017

Jamie C Harris

7

1 reference

21 June 2017

Anthony N Hollenberg

8

1 reference

21 June 2017

language of work or name

English

0 references

publication date

18 February 2014

1 reference

Molecular and Cellular Biology

21 June 2017

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

21 June 2017

34

1 reference

21 June 2017

1564-1575

1 reference

21 June 2017

9

1 reference

describes a project that uses

21 June 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3993596/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

Thyroid hormone receptor repression is linked to type I pneumocyte-associated respiratory distress syndrome

1 reference

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Molecular aspects of thyroid hormone actions

19 March 2017

1 reference

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The nuclear corepressor, NCoR, regulates thyroid hormone action in vivo

19 March 2017

1 reference

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Nuclear receptor corepressor and histone deacetylase 3 govern circadian metabolic physiology

19 March 2017

1 reference

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Combinatorial control of gene expression by nuclear receptors and coregulators

19 March 2017

1 reference

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The SMRT and N-CoR corepressors are activating cofactors for histone deacetylase 3

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Physiological and molecular basis of thyroid hormone action

19 March 2017

1 reference

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Mice deficient in the steroid receptor co-activator 1 (SRC-1) are resistant to thyroid hormone

19 March 2017

1 reference

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Determinants of coactivator LXXLL motif specificity in nuclear receptor transcriptional activation

19 March 2017

1 reference

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Role for N-CoR and histone deacetylase in Sin3-mediated transcriptional repression

19 March 2017

1 reference

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A complex containing N-CoR, mSin3 and histone deacetylase mediates transcriptional repression

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Ligand-independent repression by the thyroid hormone receptor mediated by a nuclear receptor co-repressor

19 March 2017

1 reference

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Sequence and characterization of a coactivator for the steroid hormone receptor superfamily

19 March 2017

1 reference

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Characterization of seven novel mutations of the c-erbA beta gene in unrelated kindreds with generalized thyroid hormone resistance. Evidence for two "hot spot" regions of the ligand binding domain

19 March 2017

1 reference

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Nuclear receptor coregulators: cellular and molecular biology

19 March 2017

1 reference

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Nuclear receptor repression mediated by a complex containing SMRT, mSin3A, and histone deacetylase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Novel mechanism of positive versus negative regulation by thyroid hormone receptor β1 (TRβ1) identified by genome-wide profiling of binding sites in mouse liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The thyroid axis is regulated by NCoR1 via its actions in the pituitary

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Minireview: The neural regulation of the hypothalamic-pituitary-thyroid axis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

NPY and MC4R signaling regulate thyroid hormone levels during fasting through both central and peripheral pathways

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Resistance to thyroid hormone is modulated in vivo by the nuclear receptor corepressor (NCOR1).

29 September 2017

1 reference

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PITX2 AND PITX1 regulate thyrotroph function and response to hypothyroidism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Corepressor SMRT promotes oxidative phosphorylation in adipose tissue and protects against diet-induced obesity and insulin resistance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The nuclear receptor corepressor (NCoR) controls thyroid hormone sensitivity and the set point of the hypothalamic-pituitary-thyroid axis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The interaction between nuclear receptor corepressor and histone deacetylase 3 regulates both positive and negative thyroid hormone action in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Resistance to thyroid hormone is associated with raised energy expenditure, muscle mitochondrial uncoupling, and hyperphagia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Deconstructing repression: evolving models of co-repressor action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The thyroid hormone receptor recruits NCoR via widely spaced receptor-interacting domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

In vivo interaction of steroid receptor coactivator (SRC)-1 and the activation function-2 domain of the thyroid hormone receptor (TR) beta in TRbeta E457A knock-in and SRC-1 knockout mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Minireview: Thyrotropin-releasing hormone and the thyroid hormone feedback mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Thyroid hormone resistance without mutations in thyroid hormone receptor beta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Response of SMRT (silencing mediator of retinoic acid and thyroid hormone receptor) and N-CoR (nuclear receptor corepressor) corepressors to mitogen-activated protein kinase kinase kinase cascades is determined by alternative mRNA splicing

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Negative regulation by thyroid hormone receptor requires an intact coactivator-binding surface.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Review of the in vivo functions of the p160 steroid receptor coactivator family

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Nuclear receptor coregulators: multiple modes of modification

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The specificity of interactions between nuclear hormone receptors and corepressors is mediated by distinct amino acid sequences within the interacting domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Mice with a targeted mutation in the thyroid hormone beta receptor gene exhibit impaired growth and resistance to thyroid hormone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The nuclear corepressors recognize distinct nuclear receptor complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The mechanism of action of thyroid hormones

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The SRC family of nuclear receptor coactivators

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Partial hormone resistance in mice with disruption of the steroid receptor coactivator-1 (SRC-1) gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Tertiary hypothyroidism and hyperglycemia in mice with targeted disruption of the thyrotropin-releasing hormone gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Phenotype differences of resistance to thyroid hormone in two unrelated families with an identical mutation in the thyroid hormone receptor beta gene (R320C).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The syndromes of resistance to thyroid hormone

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Cellular energy depletion resets whole-body energy by promoting coactivator-mediated dietary fuel absorption.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

STAT3 targets the regulatory regions of gluconeogenic genes in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Metabolic health and nuclear-receptor sensitivity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The genomic analysis of the impact of steroid receptor coactivators ablation on hepatic metabolism.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Dominant role of thyrotropin-releasing hormone in the hypothalamic-pituitary-thyroid axis.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Modulation by steroid receptor coactivator-1 of target-tissue responsiveness in resistance to thyroid hormone

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Thyroid hormone receptor-specific interactions with steroid receptor coactivator-1 in the pituitary

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Determination of nuclear receptor corepressor interactions with the thyroid hormone receptor

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Specificity of thyroid hormone receptor subtype and steroid receptor coactivator-1 on thyroid hormone action

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Thyroid function in mice with compound heterozygous and homozygous disruptions of SRC-1 and TIF-2 coactivators: evidence for haploinsufficiency

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Steroid receptor coactivator-1 deficiency causes variable alterations in the modulation of T(3)-regulated transcription of genes in vivo

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

The nuclear receptor corepressor (N-CoR) contains three isoleucine motifs (I/LXXII) that serve as receptor interaction domains (IDs).

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3993596

Stoichiometric and steric principles governing repression by nuclear hormone receptors

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24550004

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.00129-14

1 reference

21 June 2017

0 references

1 reference