(Q28509898)

24 January 2017

title

Mutations in Hydin impair ciliary motility in mice (English)

1 reference

HYDIN, axonemal central pair apparatus protein

24 January 2017

main subject

1 reference

GOA release 2020-03-11

author name string

Karl-Ferdinand Lechtreck

1

1 reference

24 January 2017

Philippe Delmotte

2

1 reference

24 January 2017

Michael L. Robinson

3

1 reference

24 January 2017

Michael J. Sanderson

4

1 reference

24 January 2017

George B. Witman

5

1 reference

24 January 2017

language of work or name

English

0 references

publication date

11 February 2008

1 reference

24 January 2017

published in

Journal of Cell Biology

1 reference

24 January 2017

volume

180

1 reference

24 January 2017

issue

3

1 reference

24 January 2017

page(s)

633–643

1 reference

The graded response to Sonic Hedgehog depends on cilia architecture

24 January 2017

cites work

1 reference

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19 March 2017

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Bend propagation drives central pair rotation in Chlamydomonas reinhardtii flagella

19 March 2017

1 reference

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Comparative genomics identifies a flagellar and basal body proteome that includes the BBS5 human disease gene

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Male infertility, impaired sperm motility, and hydrocephalus in mice deficient in sperm-associated antigen 6

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Loss of function of axonemal dynein Mdnah5 causes primary ciliary dyskinesia and hydrocephalus

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Chlamydomonas IFT88 and its mouse homologue, polycystic kidney disease gene tg737, are required for assembly of cilia and flagella

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Randomization of left-right asymmetry due to loss of nodal cilia generating leftward flow of extraembryonic fluid in mice lacking KIF3B motor protein

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

When cilia go bad: cilia defects and ciliopathies

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Proteomic analysis of a eukaryotic cilium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

The hydrocephalus inducing gene product, Hydin, positions axonemal central pair microtubules

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

A positive feedback mechanism governs the polarity and motion of motile cilia.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Chlamydomonas reinhardtii hydin is a central pair protein required for flagellar motility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

A 360-kb interchromosomal duplication of the human HYDIN locus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Ciliary beat frequency is maintained at a maximal rate in the small airways of mouse lung slices

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Primary ciliary dyskinesia: clinical presentation, diagnosis and genetics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Primary ciliary dyskinesia: a review

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Speculations on the evolution of 9+2 organelles and the role of central pair microtubules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

The radial spokes and central apparatus: mechano-chemical transducers that regulate flagellar motility

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Ciliary beat pattern is associated with specific ultrastructural defects in primary ciliary dyskinesia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Genetic mapping of an insertional hydrocephalus-inducing mutation allelic to hy3.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Primary ciliary dyskinesia (PCD).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Asymmetry of cilia and of mice and men.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Characterization of a Chlamydomonas insertional mutant that disrupts flagellar central pair microtubule-associated structures

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

The role of central apparatus components in flagellar motility and microtubule assembly

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Communicating hydrocephalus in dogs with congenital ciliary dysfunction.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Genetic dissection of the central pair microtubules of the flagella of Chlamydomonas reinhardtii

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Splitting the ciliary axoneme: implications for a "switch-point" model of dynein arm activity in ciliary motion

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Hydrocephalus, bronchiectasis, and ciliary aplasia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Re-evaluation of GM2346 from a del(16)(q22) to t(4;16)(q35;q22.1).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Ultrastructure of respiratory cilia of WIC-Hyd male rats. An animal model for human immotile cilia syndrome

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Chlamydomonas flagellar mutants lacking radial spokes and central tubules. Structure, composition, and function of specific axonemal components

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Pathogenesis of aqueductal occlusion in congenital murine hydrocephalus

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Cilia with defective radial spokes: a cause of human respiratory disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

The relationship between the fine structure and direction of beat in gill cilia of a lamellibranch mollusc

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Oscillations in ciliary beat frequency and intracellular calcium concentration in rabbit tracheal epithelial cells induced by ATP.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234243

Ciliary dyskinesia associated with hydrocephalus and mental retardation in a Jordanian family.

2 June 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Dysfunctional cilia lead to altered ependyma and choroid plexus function, and result in the formation of hydrocephalus

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Altered pH(i) regulation and Na(+)/HCO3(-) transporter activity in choroid plexus of cilia-defective Tg737(orpk) mutant mouse

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Flagellar motility is required for the viability of the bloodstream trypanosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Three types of cilia including a novel 9+4 axoneme on the notochordal plate of the rabbit embryo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Orientation of the central pair complex during flagellar bend formation in Chlamydomonas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Primary ciliary dyskinesia: diagnostic and phenotypic features.

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Central microtubular agenesis causing primary ciliary dyskinesia

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Abnormal central complex is a marker of severity in the presence of partial ciliary defect

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Analysis of microtubule sliding patterns in Chlamydomonas flagellar axonemes reveals dynein activity on specific doublet microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Accelerated mortality from hydrocephalus and pneumonia in mice with a combined deficiency of SPAG6 and SPAG16L reveals a functional interrelationship between the two central apparatus proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1083%2FJCB.200710162

Regulation of flagellar dynein by the axonemal central apparatus

21 January 2018

1 reference

12 December 2020

Central-pair-linked regulation of microtubule sliding by calcium in flagellar axonemes

1 reference

12 December 2020

Absent inner dynein arms in a fetus with familial hydrocephalus-situs abnormality

1 reference

12 December 2020

Dysfunction of axonemal dynein heavy chain Mdnah5 inhibits ependymal flow and reveals a novel mechanism for hydrocephalus formation

1 reference

12 December 2020

Subsidiary components of the flagella of Chlamydomonas reinhardii

1 reference

12 December 2020

Observations of the structural components of flagellar axonemes and central pair microtubules from rat sperm

1 reference

12 December 2020

Mechanism of nodal flow: a conserved symmetry breaking event in left-right axis determination

1 reference

12 December 2020

Identifiers

DOI

10.1083/JCB.200710162

1 reference

1 reference

1 reference

1 reference