(Q28533929)

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MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth

scientific article (publication date: 2013)

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scholarly article

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MicroRNA-21-3p, a berberine-induced miRNA, directly down-regulates human methionine adenosyltransferases 2A and 2B and inhibits hepatoma cell growth (English)

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1 reference

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hepatocellular carcinoma

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author name string

Ting-Fang Lo

1

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Wei-Chung Tsai

2

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Shui-Tein Chen

3

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language of work or name

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publication date

2013

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8

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e75628

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9

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Creative Commons Attribution 4.0 International

30 September 2013

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April 2022 Public Data File from Crossref

copyright status

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microRNA involvement in human cancer

1 reference

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Bioinformatic and genetic association analysis of microRNA target sites in one-carbon metabolism genes

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19 March 2017

Widespread regulatory activity of vertebrate microRNA* species

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19 March 2017

Mammalian microRNAs predominantly act to decrease target mRNA levels

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19 March 2017

The fate of miRNA* strand through evolutionary analysis: implication for degradation as merely carrier strand or potential regulatory molecule?

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Widespread changes in protein synthesis induced by microRNAs

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MicroRNA gene expression deregulation in human breast cancer

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The functions of animal microRNAs

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Liver cell proliferation requires methionine adenosyltransferase 2A mRNA up-regulation

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19 March 2017

Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II)

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19 March 2017

Differential effect of thioacetamide on hepatic methionine adenosyltransferase expression in the rat

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19 March 2017

S-adenosylmethionine synthesis: molecular mechanisms and clinical implications

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MicroRNA Target Identification-Experimental Approaches.

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Calmodulin as a potential target by which berberine induces cell cycle arrest in human hepatoma Bel7402 cells

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29 September 2017

Berberine induces caspase-independent cell death in colon tumor cells through activation of apoptosis-inducing factor

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MicroRNA expression is differentially altered by xenobiotic drugs in different human cell lines.

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29 September 2017

Berberine inhibits human hepatoma cell invasion without cytotoxicity in healthy hepatocytes

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29 September 2017

Global identification of miR-373-regulated genes in breast cancer by quantitative proteomics

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The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective

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29 September 2017

Berberine induces autophagic cell death and mitochondrial apoptosis in liver cancer cells: the cellular mechanism

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Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors.

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Coptis chinensis inhibits hepatocellular carcinoma cell growth through nonsteroidal anti-inflammatory drug-activated gene activation.

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Berberine suppresses TNF-alpha-induced MMP-9 and cell invasion through inhibition of AP-1 activity in MDA-MB-231 human breast cancer cells

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29 September 2017

Inhibition of hepatocelluar carcinoma MAT2A and MAT2beta gene expressions by single and dual small interfering RNA

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29 September 2017

Lentivirus mediated shRNA interference targeting MAT2B induces growth-inhibition and apoptosis in hepatocelluar carcinoma

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Characterization of endogenous human Argonautes and their miRNA partners in RNA silencing.

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29 September 2017

S-Adenosylmethionine in cell growth, apoptosis and liver cancer

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29 September 2017

Leptin's mitogenic effect in human liver cancer cells requires induction of both methionine adenosyltransferase 2A and 2beta

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29 September 2017

Role of S-adenosyl-L-methionine in liver health and injury

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29 September 2017

Transcription of the MAT2A gene, coding for methionine adenosyltransferase, is up-regulated by E2F and Sp1 at a chromatin level during proliferation of liver cells

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29 September 2017

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29 September 2017

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29 September 2017

Berberine induces apoptosis through a mitochondria/caspases pathway in human hepatoma cells

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29 September 2017

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Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A.

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29 September 2017

S-Adenosylmethionine: a control switch that regulates liver function.

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Role of transcriptional and posttranscriptional regulation of methionine adenosyltransferases in liver cancer progression.

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21 January 2018

Silencing MAT2A gene by RNA interference inhibited cell growth and induced apoptosis in human hepatoma cells

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21 January 2018

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21 January 2018

The role of c-Myb and Sp1 in the up-regulation of methionine adenosyltransferase 2A gene expression in human hepatocellular carcinoma

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21 January 2018

Regulation of the human MAT2B gene encoding the regulatory beta subunit of methionine adenosyltransferase, MAT II.

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21 January 2018

Methionine adenosyltransferase II beta subunit gene expression provides a proliferative advantage in human hepatoma

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12 December 2020

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10.1371/JOURNAL.PONE.0075628

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2013PLoSO...875628L

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